Sitagliptin/metformin

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Sitagliptin/Metformin

Sitagliptin/Metformin (pronunciation: sih-TAG-lih-ptin/met-FOR-min) is a combination medication used in the treatment of Type 2 diabetes. It combines two active ingredients, Sitagliptin and Metformin, to help control blood sugar levels.

Etymology

The name "Sitagliptin" is derived from the class of drugs it belongs to, known as DPP-4 inhibitors. "Metformin" is derived from the French word "metformine", which is based on the original chemical name, dimethylbiguanide.

Usage

Sitagliptin/Metformin is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. It is used when diet and exercise alone does not control blood sugar. Sitagliptin works by increasing levels of natural substances called incretins. Incretins help to control blood sugar by increasing insulin release, especially after a meal. They also decrease the amount of sugar your liver makes. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.

Side Effects

Common side effects of Sitagliptin/Metformin include nausea, vomiting, stomach upset, diarrhea, or a metallic taste in the mouth may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. If stomach symptoms return later (after taking the same dose for several days or weeks), tell your doctor right away. Stomach symptoms that occur after the first days of your treatment may be signs of lactic acidosis.

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