Tolbutamide

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Tolbutamide

Tolbutamide (pronounced: tol-BYOO-tuh-mide) is an oral hypoglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).

Etymology

The term "Tolbutamide" is derived from the chemical name p-tolylbutyramide. It was first synthesized in the 1950s as part of a series of sulfonylurea compounds.

Usage

Tolbutamide is used to control high blood sugar in people with type 2 diabetes. This medication is used when diet and exercise alone does not result in controlled blood sugar levels. Tolbutamide works by stimulating the release of your body's natural insulin.

Side Effects

Common side effects of Tolbutamide include nausea, upset stomach, or diarrhea. If these effects persist or worsen, notify your doctor promptly. This medication may cause low blood sugar (hypoglycemia) if you do not consume enough calories from food or if you do unusually heavy exercise.

Related Terms

  • Sulfonylurea: A class of oral hypoglycemic drugs that stimulate insulin release from the pancreas.
  • Hypoglycemia: A condition characterized by an abnormally low level of blood sugar.
  • Diabetes Mellitus: A group of diseases characterized by high levels of blood glucose resulting from defects in insulin production, insulin action, or both.

See Also

  • Orinase: A brand name for Tolbutamide.
  • Insulin: A hormone that regulates the amount of glucose in the blood.

External links

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