Biguanide
Biguanide
Biguanide (pronunciation: bi-gwan-ide) is a class of medications used primarily for the treatment of Type 2 diabetes.
Etymology
The term "biguanide" is derived from its chemical structure, which consists of two (bi-) guanidine groups.
Usage
Biguanides are primarily used in the treatment of Type 2 diabetes. The most commonly prescribed biguanide is metformin. Biguanides work by reducing the amount of glucose produced by the liver, increasing the uptake of glucose by muscle and fat cells, and slowing the absorption of glucose from the gut.
Related Terms
- Metformin: A biguanide medication commonly used in the treatment of Type 2 diabetes.
- Phenformin: A biguanide medication that was used in the treatment of diabetes but was withdrawn due to the risk of lactic acidosis.
- Buformin: A biguanide medication that was used in the treatment of diabetes but was withdrawn due to the risk of lactic acidosis.
- Guanidine: A compound that forms the basis of the biguanides.
Side Effects
Common side effects of biguanides include gastrointestinal upset, such as diarrhea and nausea. Rare but serious side effects include lactic acidosis, a condition in which lactic acid builds up in the bloodstream.
See Also
External links
- Medical encyclopedia article on Biguanide
- Wikipedia's article - Biguanide
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