Bunyaviridae

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Bunyaviridae

Bunyaviridae (pronounced: boo-nya-vi-ri-dee) is a family of viruses that includes several significant pathogens of humans and livestock.

Etymology

The name Bunyaviridae is derived from the location of the Bunyamwera virus, the type species of the family, which was first isolated in the Bunyamwera forest of Uganda.

Classification

Bunyaviridae is a family within the order Bunyavirales. This family includes several genera, such as Orthobunyavirus, Phlebovirus, Nairovirus, Tospovirus, and Hantavirus. Each of these genera includes several species of viruses.

Structure and Life Cycle

Viruses in the Bunyaviridae family are enveloped, with spherical to pleomorphic geometries. The life cycle of Bunyaviridae involves replication in the cytoplasm and budding at the plasma membrane of host cells.

Pathogenesis

Several viruses in the Bunyaviridae family are significant human pathogens, including the Hantavirus, which causes Hantavirus Pulmonary Syndrome (HPS) and Hemorrhagic Fever with Renal Syndrome (HFRS), and the Rift Valley Fever Virus, which causes Rift Valley Fever in livestock and humans.

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