Tymoviridae
Family of viruses
The Tymoviridae is a family of viruses in the order Tymovirales. Members of this family are known to infect plants, causing a variety of diseases that can impact agricultural productivity. The family is named after the type species, Turnip yellow mosaic virus.
Structure
Viruses in the Tymoviridae family are characterized by their non-enveloped, icosahedral capsids. The capsid is composed of a single type of protein and encapsulates a single-stranded, positive-sense RNA genome. The genome is typically monopartite and ranges from 6.0 to 7.5 kilobases in length.
Genome
The genome of Tymoviridae viruses is a single-stranded, positive-sense RNA molecule. It contains a 5' cap structure and a 3' poly-A tail, which are typical features of eukaryotic mRNA. The genome encodes several proteins, including a replicase, movement proteins, and a coat protein.
Replication
Replication of Tymoviridae viruses occurs in the cytoplasm of the host cell. The virus enters the host cell and releases its RNA genome, which is then translated by the host's ribosomes. The viral replicase synthesizes a complementary negative-sense RNA strand, which serves as a template for the production of new positive-sense RNA genomes. These genomes are packaged into new virions, which are then released to infect other cells.
Transmission
Tymoviridae viruses are primarily transmitted by insect vectors, such as beetles and aphids. The viruses can also be spread through mechanical means, such as contaminated tools or human handling of infected plants.
Host Range
The host range of Tymoviridae viruses is generally limited to dicotyledonous plants. They are known to infect a variety of economically important crops, including turnips, grapes, and citrus plants.
Symptoms
Infected plants may exhibit a range of symptoms, including mosaic patterns on leaves, chlorosis, stunting, and reduced yield. The severity of symptoms can vary depending on the virus strain, host species, and environmental conditions.
Control
Control of Tymoviridae infections involves integrated pest management strategies, including the use of resistant plant varieties, control of insect vectors, and sanitation measures to prevent mechanical transmission.
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Contributors: Prab R. Tumpati, MD