Fuselloviridae
Fuselloviridae is a family of archaeal viruses that infect members of the domain Archaea. These viruses are characterized by their unique spindle-shaped morphology and are known to infect hyperthermophilic archaea, particularly those belonging to the order Sulfolobales.
Taxonomy
The family Fuselloviridae is part of the order Ligamenvirales. It includes several genera and species, which are distinguished based on their genetic and morphological characteristics.
Morphology
Fuselloviridae viruses have a distinctive spindle-shaped or lemon-shaped appearance. They possess a double-stranded DNA genome and are enveloped by a lipid membrane. The virions typically measure about 60-100 nm in length and 40-60 nm in diameter.
Genome
The genome of Fuselloviridae viruses is composed of double-stranded DNA, which is circular and ranges from 15 to 20 kilobases in length. The genome encodes for various proteins, including those involved in DNA replication, transcription, and virion assembly.
Life Cycle
Fuselloviridae viruses infect their host cells by attaching to the cell surface and injecting their DNA into the host. The viral DNA then integrates into the host genome, where it can remain latent or initiate the production of new virions. The life cycle includes both lytic and lysogenic phases, allowing the virus to persist in the host population.
Host Range
The primary hosts for Fuselloviridae are hyperthermophilic archaea, particularly those in the order Sulfolobales. These archaea are typically found in extreme environments such as hot springs and hydrothermal vents.
Significance
Fuselloviridae viruses are of interest to researchers due to their unique morphology and life cycle, as well as their ability to infect extremophilic archaea. Studying these viruses can provide insights into viral evolution, archaeal biology, and the mechanisms of virus-host interactions in extreme environments.
See Also
References
External Links
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Contributors: Prab R. Tumpati, MD
