SARS-CoV-1

SARS-CoV-1 (Severe Acute Respiratory Syndrome Coronavirus 1) is a strain of coronavirus that caused the SARS outbreak in 2002-2004. It is an enveloped, positive-sense, single-stranded RNA virus which infects the epithelial cells within the lungs. The virus enters the host cell by binding to the angiotensin-converting enzyme 2 (ACE2) receptor.

Origin

SARS-CoV-1 is believed to have originated from bats, and was transmitted to humans via palm civets, which were sold in live-animal markets in Guangdong province, China.

Symptoms

The symptoms of SARS-CoV-1 infection include high fever, malaise, headache, body aches, and occasionally diarrhea. After 2 to 7 days, the patient may develop a dry cough and have trouble breathing.

Transmission

SARS-CoV-1 is primarily transmitted through respiratory droplets during close face-to-face contact. It can also spread by touching a contaminated surface and then touching the mouth, nose, or eyes.

Prevention and Treatment

There is currently no specific treatment for SARS-CoV-1. Management of the disease is primarily supportive, including antipyretic therapy for fever and supplemental oxygen for respiratory distress. Prevention measures include hand hygiene, use of personal protective equipment, and isolation of suspected cases.

See Also

• SARS outbreak
• Coronavirus
• Palm civet
• Angiotensin-converting enzyme 2

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