Ampullaviridae

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Overview

Electron micrograph of an Ampullavirus virion

Ampullaviridae is a family of viruses that infect archaea, specifically those within the phylum Crenarchaeota. The family is characterized by its unique virion morphology and its adaptation to extreme environments, such as hot springs and hydrothermal vents.

Morphology

The virions of Ampullaviridae are bottle-shaped, which is a distinctive feature of this family. The virion structure is composed of a long, narrow tail and a wider head, resembling an ampulla or flask. This unique morphology is thought to be an adaptation to the high-temperature environments in which these viruses are found.

Genome

Ampullaviridae viruses possess a double-stranded DNA genome. The genome is linear and relatively small, typically encoding a limited number of proteins. The genetic material is enclosed within the proteinaceous capsid, which provides protection and stability in extreme conditions.

Replication

The replication cycle of Ampullaviridae occurs within the host archaeal cell. The virus attaches to the host cell surface and injects its DNA into the host. The viral genome is then replicated using the host's machinery, and new virions are assembled within the host cell. Eventually, the host cell lyses, releasing the newly formed virions into the environment.

Host Range

Ampullaviridae specifically infects members of the Crenarchaeota, a group of archaea that thrive in high-temperature environments. These hosts are often found in geothermal areas, such as hot springs and hydrothermal vents, where they play a crucial role in the ecosystem.

Ecology

The ecological role of Ampullaviridae is not fully understood, but it is believed to influence the population dynamics of its archaeal hosts. By infecting and lysing host cells, these viruses may contribute to the recycling of nutrients and the regulation of microbial communities in extreme environments.

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Contributors: Prab R. Tumpati, MD