Lactulose

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Lactulose

Lactulose (/lækˈtjuːloʊs/) is a synthetic, non-digestible sugar used in the treatment of chronic constipation and hepatic encephalopathy, a complication of liver disease. It is a disaccharide (double sugar) that is made of fructose and galactose.

Etymology

The term "Lactulose" is derived from the names of its constituent sugars, lactose and fructose. It was first synthesized in the 1920s.

Usage

Lactulose is used in the treatment of constipation and to reduce the amount of ammonia in the blood of patients with liver disease. It works by drawing water into the bowel, which softens the stool and promotes bowel movement. In patients with liver disease, it helps to prevent the absorption of ammonia into the blood.

Related Terms

  • Constipation: A condition characterized by difficulty in passing stools or infrequent bowel movements.
  • Hepatic Encephalopathy: A decline in brain function that occurs as a result of severe liver disease.
  • Ammonia: A compound produced in the body, primarily in the intestines, during the breakdown of protein. High levels of ammonia can be harmful, particularly to the brain.
  • Liver Disease: A broad term that covers all the potential problems that cause the liver to fail to perform its designated functions.

Side Effects

Common side effects of lactulose include bloating, diarrhea, and gas. Serious side effects may include electrolyte imbalances, dehydration, and low blood sugar.

See Also

  • Disaccharide: A type of sugar that is made up of two monosaccharides.
  • Fructose: A simple sugar that is found in many plants.
  • Galactose: A simple sugar that is part of lactose.

External links

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