Trehalose

A disaccharide sugar

Chemical structure of trehalose

Trehalose is a disaccharide sugar consisting of two glucose molecules linked by an _,_-1,1-glycosidic bond. It is found naturally in many plants, fungi, and invertebrates, and is known for its ability to protect organisms from extreme conditions such as dehydration and freezing.

Structure and Properties

Trehalose is composed of two _-D-glucose units. The unique _,_-1,1 linkage distinguishes it from other disaccharides such as maltose, which has an _-1,4 linkage. This linkage gives trehalose its non-reducing properties, making it more stable than other sugars.

Trehalose is a white, crystalline powder that is moderately sweet and highly soluble in water. It is known for its ability to retain moisture, which makes it useful in food preservation and cosmetics.

Biological Role

Trehalose serves as an important source of energy and carbon in many organisms. It is particularly notable for its role in anhydrobiosis, a state of suspended animation that allows organisms to survive extreme dehydration. In this process, trehalose replaces water in cells, stabilizing proteins and membranes.

In fungi, trehalose is a major carbohydrate reserve, while in insects, it is the primary blood sugar. It is also found in bacteria and yeast, where it plays a role in stress response.

Industrial and Commercial Uses

Trehalose is used in the food industry as a sweetener and stabilizer. Its ability to protect biological structures makes it valuable in the preservation of food, pharmaceuticals, and cosmetics. It is also used in the cryopreservation of cells and tissues.

Health and Safety

Trehalose is generally recognized as safe (GRAS) by food safety authorities. It is metabolized by the enzyme trehalase, which breaks it down into two glucose molecules. However, individuals with trehalase deficiency may experience digestive issues when consuming trehalose.

Related pages

• Disaccharide
• Glucose
• Anhydrobiosis
• Maltose