Actinic elastosis

Actinic elastosis
Micrograph of actinic elastosis
Synonyms	Solar elastosis
Pronounce	N/A
Specialty	Dermatology
Symptoms	Thickened skin, wrinkles, yellow discoloration
Complications	Skin cancer
Onset	Middle age
Duration	Chronic
Types	N/A
Causes	Ultraviolet radiation exposure
Risks	Sun exposure, fair skin
Diagnosis	Clinical examination, skin biopsy
Differential diagnosis	Photoaging, cutaneous amyloidosis
Prevention	Sun protection, sunscreen
Treatment	Topical retinoids, laser therapy
Medication	N/A
Prognosis	Generally good with treatment
Frequency	Common in sun-exposed populations
Deaths	N/A

== Other names ==

Actinic elastosis is also known as solar elastosis

Micrograph of actinic keratosis

What is actinic elastosis?

As the name suggests, (actinic = SUN), it involves excess production and eventual accumulation of a protein called elastin in the dermis of the skin, or in the conjunctiva of the eye

Cause

The cause of actinic elastosis is due to cumulative effects of prolonged and excessive sun exposure

Solar elastosis

Photoaging

Actinic elastosis is part of photoaging.

Signs and symptoms

Actinic elastosis appears as thickened, dry, wrinkled skin.

Diagnosis

In the earlier stages, elastic fiber proliferation can be seen in the dermis. As it progresses, the collagen fibers of the papillary dermis and reticular dermis become replaced by thickened and curled fibers that form tangled masses and appear basophilic under routine haematoxylin and eosin staining.

Treatment

Treatment options include: dermabrasion topical application of retinoic acid carbon dioxide laser resurfacing hyaluronic acid injection into the dermis imiquimod tacrolimus ointment and topical oestrogen therapy.

Prevention

The most effective prevention strategy for photoaging remains minimization of sun exposure, through use of sunscreen and other sun exposure avoidance measures.