Template:Antifungals

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Antifungals (D01 and J02)

Wall/
membrane

Ergosterol
inhibitors

Azoles (lanosterol 14α-
demethylase inhibitors)

Imidazoles	* Topical: bifonazole^‡ butoconazole chlormidazole^‡ climbazole clotrimazole^# croconazole^‡ eberconazole econazole fenticonazole^‡ flutrimazole isoconazole ketoconazole luliconazole miconazole^# neticonazole^‡ omoconazole^‡ oxiconazole sertaconazole sulconazole tioconazole Systemic: ketoconazole
Triazoles	* Topical: efinaconazole fluconazole^# terconazole Systemic: fluconazole^# fosfluconazole fosravuconazole hexaconazole^‡ isavuconazole itraconazole^# oteseconazole posaconazole voriconazole^# Unknown: albaconazole^‡ ravuconazole^†
Thiazoles	* Topical: abafungin^‡

Polyene antimycotics
(ergosterol binding)

* Topical: hamycin^‡

natamycin
nystatin^#
Systemic: amphotericin B^#, hamycin^‡

Squalene monooxygenase
inhibitors

Allylamines	* Topical: naftifine terbinafine Systemic: terbinafine
Benzylamines	* Topical: butenafine

Others

* Topical: amorolfine

β-glucan synthase
inhibitors

* Systemic: echinocandins (anidulafungin

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	* Systemic: flucytosine^#
Mitotic inhibitors	* Systemic: griseofulvin^#
Aminoacyl tRNA synthetase inhibitors	* Topical: tavaborole

Others

* bromochlorosalicylanilide

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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