Thiazole
Thiazole
Thiazole (pronounced: /ˈθaɪəˌzoʊl/) is a type of heterocyclic compound that contains both sulfur and nitrogen in its ring structure.
Etymology
The term "thiazole" is derived from the Greek words "theion" meaning sulfur, and "azole" which is a class of compounds that contains a five-membered ring of atoms.
Structure and Properties
Thiazole is a five-membered ring compound, consisting of three carbon atoms, one nitrogen atom, and one sulfur atom. It is a colorless liquid with a pyridine-like odor and is soluble in water, alcohol, and ether. Thiazoles are known for their wide range of biological activities and are found in many important drugs and natural products.
Related Terms
- Thiazole ring: The basic structure of thiazole, consisting of a five-membered ring with one nitrogen atom, one sulfur atom, and three carbon atoms.
- Thiazolium: A positively charged ion derived from thiazole.
- Thiazolidine: A saturated ring system derived from thiazole.
- Thiazoline: A partially saturated ring system derived from thiazole.
Medical Significance
Thiazole and its derivatives have significant medical importance. They are found in many drugs, including sulfathiazole (an antibacterial drug), epothilone (an anticancer drug), and ritonavir (an antiretroviral drug). Thiazole is also a component of vitamin B1 (thiamine), which is essential for the metabolism of carbohydrates.
See Also
External links
- Medical encyclopedia article on Thiazole
- Wikipedia's article - Thiazole
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