Naftifine
Naftifine
Naftifine (pronounced: naf-ti-feen) is an antifungal medication used primarily to treat skin infections such as athlete's foot, jock itch, and ringworm. It belongs to the class of drugs known as allylamine antifungals.
Etymology
The term "Naftifine" is derived from the chemical name N-methyl-N-(1-naphthylmethyl)-3-phenyl-2-propen-1-amine. The prefix "Naf-" is derived from "naphthyl", a term referring to the two-ring structure present in the compound. The suffix "-tine" is a common ending for medications, particularly antifungal agents.
Usage
Naftifine is typically applied topically in the form of a cream or gel. It works by inhibiting the enzyme squalene epoxidase, which is necessary for the synthesis of ergosterol, a key component of fungal cell membranes. By disrupting this process, Naftifine causes the fungal cells to die, thereby treating the infection.
Related Terms
- Allylamine: A class of antifungal drugs that includes Naftifine.
- Squalene epoxidase: An enzyme inhibited by Naftifine.
- Ergosterol: A component of fungal cell membranes disrupted by Naftifine.
Side Effects
Common side effects of Naftifine include redness, itching, swelling, or a burning sensation at the site of application. If these side effects persist or worsen, it is recommended to consult a healthcare professional.
Precautions
Before using Naftifine, inform your doctor or pharmacist if you are allergic to it; or to other allylamine antifungals (such as terbinafine); or if you have any other allergies.
External links
- Medical encyclopedia article on Naftifine
- Wikipedia's article - Naftifine
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