Nephrosis
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Nephrosis | |
|---|---|
| Synonyms | Nephrotic syndrome |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Edema, proteinuria, hypoalbuminemia, hyperlipidemia |
| Complications | Infection, thrombosis, acute kidney injury |
| Onset | Variable, often in childhood |
| Duration | Chronic |
| Types | N/A |
| Causes | Diabetes mellitus, lupus, amyloidosis, minimal change disease |
| Risks | Hypertension, obesity, family history |
| Diagnosis | Urinalysis, blood test, kidney biopsy |
| Differential diagnosis | Nephritis, glomerulonephritis, chronic kidney disease |
| Prevention | N/A |
| Treatment | Corticosteroids, immunosuppressants, diuretics, ACE inhibitors |
| Medication | Prednisone, cyclophosphamide, furosemide, enalapril |
| Prognosis | Variable, depends on underlying cause |
| Frequency | Common |
| Deaths | Varies by region and underlying cause |
Nephrosis is a non-inflammatory kidney condition characterized by damage to the tubules in the kidneys. It is often associated with large amounts of protein loss in the urine, low blood protein levels, high cholesterol levels, and swelling. Nephrosis is also known as nephrotic syndrome.
Causes
Nephrosis can be caused by a variety of conditions, including diabetes, lupus, and certain drugs. It can also be caused by infections such as HIV, hepatitis, and malaria. In some cases, the cause of nephrosis is unknown.
Symptoms
The symptoms of nephrosis can vary, but often include swelling, particularly in the legs and around the eyes, foamy urine, weight gain, and fatigue. In severe cases, it can lead to kidney failure.
Diagnosis
Nephrosis is typically diagnosed through a combination of physical examination, urine tests, blood tests, and sometimes a kidney biopsy. The diagnosis is often confirmed by finding high levels of protein in the urine and low levels of protein in the blood.
Treatment
The treatment for nephrosis typically involves addressing the underlying cause of the condition. This may involve medication to control diabetes, lupus, or other conditions, or it may involve treating any infections that may be present. In some cases, dietary changes may also be recommended.
Prognosis
The prognosis for nephrosis can vary depending on the underlying cause of the condition and the individual's overall health. In some cases, with appropriate treatment, the condition can be managed and the individual can lead a normal life. In other cases, the condition can lead to kidney failure and may require dialysis or a kidney transplant.
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Contributors: Prab R. Tumpati, MD