Microscopic polyangiitis
Microscopic polyangiitis (pronunciation: mi·cro·scop·ic poly·an·gi·i·tis) is a rare autoimmune disease characterized by inflammation of small and medium-sized blood vessels (vasculitis) in the body.
Etymology
The term "Microscopic polyangiitis" is derived from the Greek words "micros" meaning small, "poly" meaning many, and "angiitis" meaning inflammation of blood vessels.
Definition
Microscopic polyangiitis is a systemic vasculitis affecting small vessels, predominantly capillaries, venules, or arterioles. It is associated with antineutrophil cytoplasmic antibodies (ANCA), particularly those targeting myeloperoxidase (MPO-ANCA).
Symptoms
The symptoms of microscopic polyangiitis can vary greatly from person to person, but may include fatigue, weight loss, fever, muscle and joint pain, nerve damage, and kidney problems.
Diagnosis
Diagnosis of microscopic polyangiitis is often challenging due to its nonspecific symptoms. It is typically confirmed through a combination of blood tests, imaging studies, and sometimes a biopsy of affected tissue.
Treatment
Treatment for microscopic polyangiitis typically involves medications to suppress the immune system and reduce inflammation, such as corticosteroids and immunosuppressants.
Prognosis
The prognosis for individuals with microscopic polyangiitis can vary. With early diagnosis and appropriate treatment, many people can lead a normal life. However, the disease can cause serious complications if not treated promptly.
See also
- Vasculitis
- Autoimmune disease
- Antineutrophil cytoplasmic antibody
- Corticosteroids
- Immunosuppressants
External links
- Medical encyclopedia article on Microscopic polyangiitis
- Wikipedia's article - Microscopic polyangiitis
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