Eosinophilic granulomatosis with polyangiitis
Eosinophilic Granulomatosis with Polyangiitis (pronounced: ee-oh-sin-oh-fil-ik gran-yuh-loh-muh-toh-sis with pol-ee-an-jee-eye-tis), formerly known as Churg-Strauss Syndrome, is a rare type of autoimmune disease that causes inflammation of small and medium-sized blood vessels (vasculitis) in persons with a history of airway allergic hypersensitivity (atopy).
Etymology
The term "Eosinophilic Granulomatosis with Polyangiitis" is derived from the Greek words "eosin" meaning "dawn-colored", "granuloma" meaning "small nodular inflammation", and "polyangiitis" meaning "inflammation of many blood vessels". The disease was first described by Jacob Churg and Lotte Strauss in 1951, hence the former name "Churg-Strauss Syndrome".
Symptoms
The symptoms of Eosinophilic Granulomatosis with Polyangiitis can vary greatly from person to person, but may include asthma, sinusitis, skin rashes, and abdominal pain. In severe cases, it can affect the heart, kidneys, and nervous system.
Diagnosis
Diagnosis of Eosinophilic Granulomatosis with Polyangiitis involves a combination of clinical evaluation, laboratory tests including blood tests for eosinophils and ANCA, and imaging studies. A biopsy of affected tissue may also be performed.
Treatment
Treatment typically involves medications to reduce inflammation and suppress the immune system, such as corticosteroids and immunosuppressants. In severe cases, chemotherapy may be used.
Prognosis
The prognosis for Eosinophilic Granulomatosis with Polyangiitis varies depending on the organs involved and the patient's response to treatment. With appropriate treatment, most people can lead a normal life.
See Also
External links
- Medical encyclopedia article on Eosinophilic granulomatosis with polyangiitis
- Wikipedia's article - Eosinophilic granulomatosis with polyangiitis
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