Hypereosinophilic syndrome

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Hypereosinophilic Syndrome

Hypereosinophilic syndrome (pronunciation: hi-per-ee-oh-sin-oh-fil-ik sin-drome) is a rare, often chronic disorder characterized by the overproduction of eosinophils in the blood and tissues.

Etymology

The term "hypereosinophilic syndrome" is derived from the Greek words "hyper" meaning over or above, "eosin" referring to the rose-colored staining of eosinophils under a microscope, and "philic" meaning loving. The term "syndrome" is derived from the Greek word "syndromē" which means concurrence of symptoms, or a disease identified by a set of symptoms.

Definition

Hypereosinophilic syndrome is a condition that can affect multiple organ systems including the heart, lungs, skin, nervous system, and gastrointestinal tract. It is characterized by a persistently high number of eosinophils in the blood (hypereosinophilia), and damage to organs from the release of proteins from the eosinophils.

Symptoms

Symptoms of hypereosinophilic syndrome can vary widely depending on which part of the body is affected. Common symptoms include fatigue, cough, rash, fever, and abdominal pain. In severe cases, it can lead to life-threatening complications such as heart disease and stroke.

Diagnosis

Diagnosis of hypereosinophilic syndrome typically involves blood tests to measure the number of eosinophils. Other tests such as imaging studies, biopsy, and genetic testing may be used to confirm the diagnosis and assess the extent of organ involvement.

Treatment

Treatment for hypereosinophilic syndrome typically involves medications to reduce the number of eosinophils in the blood and prevent organ damage. This may include corticosteroids, chemotherapy drugs, and immunomodulatory drugs.

Related Terms

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