Myocarditis
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Myocarditis | |
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Synonyms | Inflammatory cardiomyopathy |
Pronounce | N/A |
Specialty | N/A |
Symptoms | Chest pain, shortness of breath, fatigue, arrhythmias |
Complications | Heart failure, sudden cardiac death |
Onset | Variable |
Duration | Variable |
Types | N/A |
Causes | Viral infection, bacterial infection, autoimmune disease, toxins |
Risks | Viral infections, autoimmune disorders, toxic substances |
Diagnosis | Electrocardiogram, blood tests, cardiac MRI, endomyocardial biopsy |
Differential diagnosis | Acute coronary syndrome, pericarditis, cardiomyopathy |
Prevention | N/A |
Treatment | Medications, supportive care, heart transplant |
Medication | ACE inhibitors, beta blockers, diuretics |
Prognosis | Variable; can be self-limiting or lead to chronic heart failure |
Frequency | Rare |
Deaths | N/A |
Myocarditis is inflammation of the heart muscle.
Causes
Myocarditis can be caused by a virus, certain [[drugs, or radiation therapy.
Infectious myocarditis
Myocarditis is most commonly caused by an infection such as influenza (flu) virus, coxsackievirus, parovirus, cytomegalovirus, adenovirus, and others that reaches the heart.
Symptoms
- Chest pain that may resemble a heart attack
- Fatigue or listlessness
- Fever and other signs of infection
- Joint pain or swelling
- Leg swelling
- Pale, cool hands and feet
- Rapid breathing
- Rapid heart rate
- Fainting, often related to irregular heart rhythms
- Low urine output
Work up
Myocarditis can be hard to diagnose because the signs and symptoms often mimic those of other heart and lung diseases, or a bad case of the flu. Physical exam There may be signs of infection, including fever and rashes. Imaging studies
- A chest x-ray can show enlargement (swelling) of the heart.
- Electrocardiogram may also be done to help make the diagnosis.
- Heart biopsy is the most accurate way to confirm the diagnosis, but it is not always needed
- Other tests that may be needed include:
- Blood cultures to check for infection
- Blood tests to look for antibodies against viruses or the heart muscle itself
- Blood tests to check liver and kidney function
- Complete blood count
- Special tests to check for the presence of viruses in the blood (viral PCR)
Treatment
- Treatment is aimed at the cause of the problem, and may involve:
- Antibiotics to fight bacterial infection
- Steroids to reduce swelling
- Intravenous immunoglobulin (IVIG)
- Diuretics to remove excess water from the body
- Low-salt diet
- Reduced activity
- Rarely, a heart transplant may be needed.
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Contributors: Prab R. Tumpati, MD