Template:Glucocorticoidics: Difference between revisions

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#REDIRECT [[Template:Glucocorticoid receptor modulators]]
{{Navbox
| name  = Glucocorticoid receptor modulators
| title = [[Glucocorticoid receptor]] [[receptor modulator|modulator]]s
| bodyclass = hlist
| state = {{{state<includeonly>|collapsed</includeonly>}}}
| groupstyle = text-align:center;
 
  | group1 = {{abbrlink|GR|Glucocorticoid receptor}}
  | list1  = {{Navbox|subgroup
  | groupstyle = text-align:center
  | groupwidth = 6em;
 
    | group1 = [[Glucocorticoid|Agonist]]s
    | list1  =
* ''Cortisol-like and related (16-unsubstituted):'' [[Tetrahydrocorticosterone|3α,5α-Tetrahydrocorticosterone]]
* [[5α-Dihydrocorticosterone]]
* [[9α-Fluorocortisone|9α-Fluorocortisone (alfluorone)]]
* [[11-Dehydrocorticosterone|11-Dehydrocorticosterone (11-oxocorticosterone, 17-deoxycortisone)]]
** [[11-Dehydrocorticosterone acetate]]<!--11-Dehydrocorticosterone 21-acetate-->
* [[11-Deoxycorticosterone|11-Deoxycorticosterone (desoxycortone, deoxycortone, desoxycorticosterone)]]
** [[List of corticosteroid esters#Desoxycortone esters|Desoxycortone esters]]
* [[11-Deoxycortisol|11-Deoxycortisol (cortodoxone, cortexolone)]]
** [[Cortifen|Cortifen (cortiphen, kortifen)]]
** [[Cortodoxone acetate]]<!--Cortodoxone 21-acetate-->
* [[21-Deoxycortisol]]
* [[Δ7-Prednisolone|Δ<sup>7</sup>-Prednisolone]]
** [[Δ7-Prednisolone 21-acetate|Δ<sup>7</sup>-Prednisolone 21-acetate]]
* [[Amebucort]]
* [[Chloroprednisone]]
** [[Chloroprednisone acetate]]<!--Chloroprednisone 21-acetate-->
* [[Cloprednol]]
** [[Cloprednol acetate]]<!--Cloprednol 21-acetate-->
* [[Corticosterone]]
** [[Corticosterone acetate]]<!--Corticosterone 21-acetate-->
** [[Corticosterone benzoate]]<!--Corticosterone 21-benzoate-->
* [[Cortisol]] ([[hydrocortisone]])
** [[Benzodrocortisone|Benzodrocortisone (hydrocortisone benzoate)]]<!--Hydrocortisone 17α-benzoate-->
** [[Hydrocortamate|Hydrocortamate (hydrocortisone diethylaminoacetate)]]<!--Hydrocortisone 21-(diethylaminoacetate)-->
** [[List of corticosteroid esters#Hydrocortisone esters|Hydrocortisone esters]]
* [[Cortisone]]
** [[Cortisone acetate]]<!--Cortisone 21-acetate-->
* [[Deprodone]]
** [[Deprodone propionate]]<!--Deprodone 17α-propionate-->
* [[Dichlorisone]]
** [[Dichlorisone acetate]]<!--Dichlorisone 21-acetate-->
** [[Dichlorisone diacetate]]<!--Dichlorisone 17α,21-diacetate-->
* [[Difluprednate]]
* [[Endrisone|Endrisone (endrysone)]]
* [[Etiprednol]]
** [[Etiprednol dicloacetate|Etiprednol dicloacetate (etiprednol dichloroacetate)]]<!--Etiprednol 17α-(dichloroacetate)-->
* [[Fludrocortisone|Fludrocortisone (fludrocortone)]]
** [[Fludrocortisone acetate]]<!--Fludrocortisone 21-acetate-->
* [[Fluorometholone]]
** [[Fluorometholone acetate]]<!--Fluorometholone 17α-acetate-->
* [[Fluperolone]]
** [[Fluperolone acetate]]<!--Fluperolone 17α-acetate-->
* [[Fluprednisolone]]
** [[List of corticosteroid esters#Fluprednisolone esters|Fluprednisolone esters]]
* [[Halopredone]]
** [[Halopredone acetate|Halopredone acetate (halopredone diacetate)]]<!--Halopredone 17α,21-diacetate-->
* [[Isoflupredone|Isoflupredone (9α-fluoroprednisolone)]]
** [[Isoflupredone acetate]]<!--Isoflupredone 21-acetate-->
* [[Loteprednol]]
* [[Mazipredone|Mazipredone (depersolone)]]
* [[Medrysone]]
* [[Methylprednisolone]]
** [[List of corticosteroid esters#Methylprednisolone esters|Methylprednisolone esters]]
* [[Prebediolone]]
** [[Prebediolone acetate]]<!--Prebediolone 21-acetate-->
* [[Prednisolone]]
** [[Prednazate]]<!--Prednisolone 21-(3-carboxypropionate) compound with perphenazine-->
** [[Prednazoline]]<!--Prednisolone 21-(dihydrogen phosphate) compound with fenoxazoline-->
** [[Prednicarbate|Prednicarbate (prednisolone ethylcarbonate propionate)]]<!--Prednisolone 17α-(ethylcarbonate) 21-propionate-->
** [[Prednimustine]]<!--Prednisolone 21-ester of chlorambucil--->
** [[Prednisolamate|Prednisolamate (prednisolone diethylaminoacetate)]]<!--Prednisolone 21-(diethylaminoacetate)-->
** [[List of corticosteroid esters#Prednisolone esters|Prednisolone esters]]
* [[Prednisone]]
** [[List of corticosteroid esters#Prednisone esters|Prednisone esters]]
* [[Pregnenolone]]
** [[Pregnenolone acetate]]<!--Pregnenolone 3β-acetate-->
** [[Pregnenolone succinate|Pregnenolone succinate (pregnenolone hemisuccinate)]]<!--Pregnenolone 3β-(hydrogen succinate)-->
* [[Resocortol]]
* [[Tipredane]]
* [[Tixocortol]]
** [[Butixocort|Butixocort (tixocortol butyrate)]]
*** [[Butixocort propionate]]<!--Butixocort 21-propionate-->
** [[Tixocortol pivalate]]<!--Tixocortol 21-pivalate-->
 
* ''Methasones and related (16-substituted):'' [[16α-Methyl-11-oxoprednisolone]]<!--17α,21-Dihydroxy-16α-methylpregna-1,4-diene-3,11,20-trione-->
* [[Alclometasone]]
** [[Alclometasone dipropionate]]<!--Alclometasone 17α,21-dipropionate-->
* [[Amelometasone]]
* [[Beclometasone|Beclometasone (beclomethasone)]]
** [[List of corticosteroid esters#Beclometasone esters|Beclometasone esters]]
* [[Betamethasone|Betamethasone (betametasone)]]
** [[List of corticosteroid esters#Betamethasone esters|Betamethasone esters]]
** [[Cortobenzolone|Cortobenzolone (betamethasone salicylate)]]
* [[Ciclometasone|Ciclometasone (ciclomethasone, cyclomethasone)]]
* [[Clobetasol]]
** [[Clobetasol propionate]]<!--Clobetasol 17α-propionate-->
* [[Clobetasone]]
** [[Clobetasone butyrate]]<!--Clobetasone 17α-butyrate-->
* [[Clocortolone]]
** [[List of corticosteroid esters#Clocortolone esters|Clocortolone esters]]
* [[Cloticasone]]
** [[Cloticasone propionate]]<!--Cloticasone 17α-propionate-->
* [[Cormetasone|Cormetasone (cormethasone)]]
** [[Cormetasone acetate]]<!--Cormetasone 21-acetate-->
* [[Descinolone]]
* [[Desoximetasone|Desoximetasone (desoxymethasone)]]
* [[Dexamethasone|Dexamethasone (dexametasone)]]
** [[List of corticosteroid esters#Dexamethasone esters|Dexamethasone esters]]
* [[Diflorasone]]
** [[Diflorasone diacetate]]<!--Diflorasone 17α,21-diacetate-->
* [[Diflucortolone]]
** [[Diflucortolone pivalate]]<!--Diflucortolone 21-pivalate-->
** [[Diflucortolone valerate]]<!--Diflucortolone 21-valerate-->
* [[Dimesone]]
** [[Dimesone acetate]]<!--Dimesone 21-acetate-->
* [[Doxibetasol|Doxibetasol (doxybetasol)]]
* [[Fluclorolone]]
* [[Flumetasone|Flumetasone (flumethasone)]]
** [[Flumetasone acetate]]<!--Flumetasone 21-acetate-->
** [[Flumetasone pivalate]]<!--Flumetasone 21-pivalate-->
* [[Fluocinolone]]
* [[Fluocortin]]
** [[Fluocortin butyl|Fluocortin butyl (fluocortin butylate)]]<!--Fluocortin 21-butylate-->
* [[Fluocortolone]]
** [[List of corticosteroid esters#Fluocortolone esters|Fluocortolone esters]]
* [[Fluprednidene|Fluprednidene (fluprednylidene)]]
** [[Fluprednidene acetate]]<!--Fluprednidene 21-acetate-->
* Fluticasone
** [[Fluticasone furoate]]<!--Fluticasone 17α-(2-furoate)-->
** [[Fluticasone propionate]]<!--Fluticasone 17α-propionate-->
* [[Halocortolone]]
* [[Halometasone]]
* [[Icometasone]]
** [[Icometasone enbutate|Icometasone enbutate (icometasone butyrate acetate)]]<!--Icometasone 17α-butyrate 21-acetate-->
* [[Isoprednidene]]
* [[Locicortolone|Locicortolone (locicortone)]]
** [[Locicortolone dicibate|Locicortolone dicibate (locicortone dicibate)]]<!--Locicortolone 21-dicibate (locicortolone 21-(dicyclohexylmethylcarbonate))-->
* [[Meclorisone]]
** [[Meclorisone dibutyrate]]<!--Meclorisone 17α,21-dibutyrate-->
* [[Meprednisone|Meprednisone (methylprednisone)]]
** [[Meprednisone acetate]]<!--Meprednisone 21-acetate-->
** [[Meprednisone hydrogen succinate|Meprednisone hydrogen succinate (methylprednisone hemisuccinate)]]<!--Meprednisone 21-(hemisuccinate)-->
* [[Mometasone]]
** [[Mometasone furoate]]<!--Mometasone 17α-(2-furoate)-->
* [[Paramethasone]]
** [[Paramethasone acetate]]<!--Paramethasone 21-acetate-->
** [[Paramethasone disodium phosphate]]<!--Paramethasone 21-(disodium phosphate)-->
** [[Paramethasone phosphate]]<!--Paramethasone 21-phosphate-->
* [[Prednylidene]]
** [[Prednylidene diethylaminoacetate]]<!--Prednylidene 21-(diethylaminoacetate)-->
* [[Rimexolone]]
* [[Ticabesone]]
** [[Ticabesone propionate]]<!--Ticabesone 17α-propionate-->
* [[Timobesone]]
** [[Timobesone acetate]]<!--Timobesone 17α-acetate-->
* [[Triamcinolone]]
** [[Triamcinolone diacetate]]<!--Triamcinolone 16α,21-diacetate-->
* [[Ulobetasol|Ulobetasol (halobetasol)]]
** [[Ulobetasol propionate]]<!--Ulobetasol 17α-propionate-->
* [[Vamorolone]]
 
* ''Cyclic ketals (16,17-cyclized):'' [[Acrocinonide|Acrocinonide (triamcinolone acroleinide)]]
* [[Amcinafal|Amcinafal (triamcinolone pentanonide)]]
* [[Amcinafide|Amcinafide (triamcinolone acetophenide)]]
* [[Amcinonide|Amcinonide (triamcinolone acetate cyclopentanonide)]]
* [[Budesonide]]
* [[Ciclesonide]]
* [[Cicortonide]]
* [[Deflazacort|Deflazacort (azacort)]]
* [[Descinolone acetonide]]<!--Descinolone 16α,17α-acetonide-->
* [[Desonide|Desonide (hydroxyprednisolone acetonide)]]
** [[Desonide disodium phosphate]]<!--Desonide 21-(disodium phosphate)-->
** [[Desonide pivalate]]<!--Desonide 21-pivalate-->
* [[Dexbudesonide]]
* [[Drocinonide]]
** [[Drocinonide phosphate]]<!--Drocinonide 21-phosphate-->
* [[Fluazacort]]
* [[Fluclorolone acetonide|Fluclorolone acetonide (flucloronide)]]<!--Fluclorolone 16α,17α-acetonide-->
* [[Fludroxycortide|Fludroxycortide (flurandrenolone, flurandrenolide)]]
* [[Flumoxonide]]
* [[Flunisolide]]
** [[Flunisolide acetate]]<!--Flunisolide 21-acetate-->
* [[Fluocinolone acetonide]]<!--Fluocinolone 16α,17α-acetonide-->
** [[Ciprocinonide|Ciprocinonide (fluocinolone acetonide cyclopropylcarboxylate)]]<!--Fluocinolone 16α,17α-acetonide 21-cyclopropylcarboxylate-->
** [[Fluocinonide|Fluocinonide (fluocinolide, fluocinolone acetonide acetate)]]<!--Fluocinolone acetonide 21-acetate-->
** [[Procinonide|Procinonide (fluocinolone acetonide propionate)]]<!--Fluocinolone acetonide 21-propionate-->
* [[Formocortal]]
* [[Halcinonide]]
* [[Itrocinonide]]
* [[Rofleponide]]
** [[Rofleponide palmitate]]<!--Rofleponide 11β-palmitate-->
* [[Tralonide]]
* [[Triamcinolone acetonide]]<!--Triamcinolone 16α,17α-acetonide-->
** [[Flupamesone|Flupamesone (triamcinolone acetonide metembonate)]]
** [[List of corticosteroid esters#Triamcinolone acetonide esters|Triamcinolone acetonide esters]]
* [[Triamcinolone aminobenzal benzamidoisobutyrate|Triamcinolone aminobenzal benzamidoisobutyrate (TBI-PAB)]]<!--51241-99-7; Triamcinolone 16α,17α-(((4-(dimethylamino)phenyl)methylene)dioxy) 21-(benzoyl-β-aminoisobutyrate)-->
* [[Triclonide]]
 
* ''Others/atypical (other expanded steroid ring systems, homosteroids, and non-pregnane steroids):'' [[Cortisuzol]]
* [[Cortivazol]]
* [[Domoprednate]]
* [[Naflocort]]
* [[Nicocortonide]]
** [[Nicocortonide acetate]]<!--Nicocortonide 21-acetate-->
* [[Nivacortol|Nivacortol (nivazol)]]
* [[Oxisopred]]
* [[RU-26988]]
* [[RU-28362]]
 
* ''Non-corticosteroids with some glucocorticoid activity:'' [[15β-Hydroxycyproterone acetate]]
* [[17α-Hydroxyprogesterone]]
* [[Bromoketoprogesterone]]
* [[Chlormadinone acetate]]
* [[Cyproterone]]
* [[Cyproterone acetate]]
* [[Danazol]]
* [[Delmadinone acetate]]
* [[Desogestrel]]
* [[DU-41165]]
* [[Etonogestrel]]
* [[Flugestone]]
* [[Flugestone acetate|Flugestone acetate (flurogestone acetate)]]
* [[Fluoromedroxyprogesterone acetate]]
* [[Fluoxymesterone]]
* [[Gestodene]]
* [[Medrogestone]]
* [[Medroxyprogesterone acetate]]
* [[Megestrol acetate]]
* [[Metribolone]]
* [[Norgestomet]]
* [[Osaterone acetate]]
* [[Progesterone]]
* [[Promegestone]]
* [[RU-2309]]
* [[Quingestrone]]
* [[Segesterone acetate|Segesterone acetate (nestorone)]]
* [[Tetrahydrogestrinone]]
 
* ''Nonsteroidal glucocorticoids:'' [[AZD-5423]]
* [[GSK-9027]]
 
  | group2 = Mixed<br />({{abbrlink|SEGRMs|Selective glucocorticoid receptor agonists}})
  | list2  =
* [[Dagrocorat]]
* [[Fosdagrocorat]]
* [[Mapracorat]]
 
    | group3 = [[Antiglucocorticoid|Antagonist]]s
    | list3  =
* [[7α-Hydroxy-DHEA]]
* [[17α-Methylprogesterone]]
* [[Aglepristone]]
* [[Asoprisnil]]
* [[Asoprisnil ecamate]]
* [[C108297]]
* [[C113176]]
* [[CORT-108297]]
* [[Cyproterone acetate]]
* [[Exicorilant|Exicorilant (CORT-125281)]]
* [[Guggulsterone]]
* [[Ketoconazole]]
* [[Lilopristone]]
* [[LLY-2707]]<!--Non-steroidal-->
* [[Metapristone|Metapristone (RU-42633)]]
* [[Miconazole]]
* [[Mifepristone|Mifepristone (RU-486)]]
* [[Miricorilant|Miricorilant (CORT-118335)]]
* [[Onapristone]]
* [[ORG-34116]]
* [[ORG-34517|ORG-34517 (SCH-900636)]]
* [[Org 34850|ORG-34850]]
* [[Pregnenolone 16α-carbonitrile]]
* [[Relacorilant|Relacorilant (CORT-125134)]]
* [[RTI 3021–012]]
* [[RTI 3021–022]]
* [[Telapristone]]
* [[Tibolone]]
* [[Toripristone]]
* [[Ulipristal acetate]]
 
    | group4 = Others
    | list4  =
* ''Antisense oligonucleotides:'' [[IONIS-GCCRRx|IONIS-GCCR<sub>Rx</sub> (ISIS-426115)]]
 
  }}
 
  | below =
;See also
: [[Template:Receptor modulators|Receptor/signaling modulators]]
: [[Template:Glucocorticoids and antiglucocorticoids|Glucocorticoids and antiglucocorticoids]]
: [[Template:Mineralocorticoid receptor modulators|Mineralocorticoid receptor modulators]]  
: [[List of corticosteroids]]
 
}}
<noinclude>
{{collapsible option}}
[[Category:Drug templates by receptor, channel, or pump]]
[[Category:Glucocorticoids]]
</noinclude>
{{no-index-template}}

Revision as of 09:27, 30 April 2024

Glucocorticoid receptor modulators
GR
Agonists
* Cortisol-like and related (16-unsubstituted): 3α,5α-Tetrahydrocorticosterone
Mixed
(SEGRMs )
Antagonists
Others
* Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)


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