Triamcinolone diacetate

From WikiMD's medical encyclopedia

A synthetic corticosteroid used in various medical treatments


Triamcinolone diacetate
INN
Drug class
Routes of administration
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status
CAS Number 3870-07-3
PubChem 5281060
DrugBank
ChemSpider 4447590
KEGG


Triamcinolone diacetate is a synthetic corticosteroid used in the treatment of various inflammatory and autoimmune conditions. It is a derivative of triamcinolone, modified to enhance its pharmacological properties.

Pharmacology

Triamcinolone diacetate functions by mimicking the effects of cortisol, a naturally occurring hormone produced by the adrenal glands. It exerts its effects by binding to glucocorticoid receptors, leading to a decrease in the production of inflammatory mediators and suppression of the immune response.

Medical uses

Triamcinolone diacetate is used in the management of conditions such as allergic reactions, asthma, rheumatoid arthritis, and dermatological disorders. It is often administered via injection to provide localized anti-inflammatory effects.

Side effects

Common side effects of triamcinolone diacetate include skin thinning, bruising, and hyperglycemia. Long-term use can lead to more serious effects such as osteoporosis, adrenal suppression, and Cushing's syndrome.

Mechanism of action

The drug works by inhibiting the release of substances in the body that cause inflammation. It reduces the activity of the immune system by interfering with the function of white blood cells and other components of the immune response.

Related pages

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Triamcinolone diacetate

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