Teriflunomide

Teriflunomide

Teriflunomide (pronounced as ter-i-floo-no-mide) is an immunomodulatory drug used primarily in the treatment of multiple sclerosis (MS). It is marketed under the brand name Aubagio by Sanofi.

Etymology

The name "Teriflunomide" is derived from its chemical structure, which is a derivative of isoxazole and benzene rings with a fluorine atom and an amide group.

Pharmacology

Teriflunomide works by inhibiting the enzyme dihydroorotate dehydrogenase, which plays a key role in the proliferation of lymphocytes. By inhibiting this enzyme, teriflunomide reduces the number of activated lymphocytes in the central nervous system, thereby reducing inflammation and nerve damage.

Usage

Teriflunomide is used in the treatment of relapsing forms of multiple sclerosis. It is taken orally, once a day. The most common side effects include nausea, diarrhea, and hair thinning.

Related Terms

• Immunomodulatory
• Multiple sclerosis
• Sanofi
• Isoxazole
• Benzene
• Fluorine
• Amide
• Dihydroorotate dehydrogenase
• Lymphocytes
• Central nervous system
• Nausea
• Diarrhea
• Hair thinning

External links

• Medical encyclopedia article on Teriflunomide
• Wikipedia's article - Teriflunomide

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