Uhthoff's phenomenon

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Uhthoff's phenomenon
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Temporary worsening of neurological symptoms
Complications	N/A
Onset	Typically occurs with heat or exercise
Duration	Symptoms usually resolve with cooling or rest
Types	N/A
Causes	Multiple sclerosis, other demyelinating diseases
Risks	Heat exposure, physical exertion
Diagnosis	Clinical evaluation, patient history
Differential diagnosis	Relapse of multiple sclerosis, Lhermitte's sign
Prevention	N/A
Treatment	Avoidance of heat, cooling strategies
Medication	N/A
Prognosis	Symptoms are reversible with cooling
Frequency	Common in individuals with multiple sclerosis
Deaths	N/A

Uhthoff's phenomenon is a symptom that is commonly associated with multiple sclerosis (MS). It is characterized by a temporary worsening of MS symptoms due to an increase in body temperature. This can be caused by exercise, hot weather, or a fever. The phenomenon is named after Wilhelm Uhthoff, a German ophthalmologist who first described the symptom in 1890.

Symptoms

The symptoms of Uhthoff's phenomenon can vary depending on the individual and the severity of their MS. However, common symptoms include:

• Fatigue
• Blurred vision
• Muscle weakness
• Numbness
• Cognitive dysfunction

These symptoms typically worsen with an increase in body temperature and improve once the body cools down.

Causes

Uhthoff's phenomenon is caused by an increase in body temperature, which can disrupt the transmission of nerve signals in people with MS. This is because heat can cause the already damaged myelin sheath to function less efficiently, leading to a temporary worsening of symptoms.

Treatment

Treatment for Uhthoff's phenomenon typically involves managing the underlying MS and avoiding triggers that can increase body temperature. This can include:

• Staying cool: This can involve staying in air-conditioned environments during hot weather, drinking cold fluids, and using cooling products such as vests and neck wraps.
• Managing MS: This can involve taking medication to manage MS symptoms and slow the progression of the disease.

See also

• Multiple Sclerosis
• Neurology
• Wilhelm Uhthoff

References

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