Peficitinib

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Peficitinib

Peficitinib (pronunciation: peh-fih-sit-in-ib) is an oral Janus kinase inhibitor used in the treatment of rheumatoid arthritis. It is developed by Astellas Pharma and is marketed under the brand name Smyraf.

Etymology

The name "Peficitinib" is derived from the drug's mechanism of action. "Pefi" is an abbreviation of "Peficitinib", "tinib" is a common suffix for kinase inhibitors, indicating the drug's function.

Mechanism of Action

Peficitinib works by inhibiting the activity of Janus kinase (JAK), a type of enzyme that plays a crucial role in the signaling pathways for various immune and inflammatory responses. By blocking JAK, Peficitinib helps to reduce inflammation and other symptoms associated with rheumatoid arthritis.

Related Terms

  • Janus kinase inhibitor: A type of drug that blocks the action of Janus kinases.
  • Rheumatoid arthritis: A chronic inflammatory disorder affecting many joints, including those in the hands and feet.
  • Astellas Pharma: A Japanese multinational pharmaceutical company, the developer of Peficitinib.

See Also

External links

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