11-Nor-9-carboxy-THC

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11-Nor-9-carboxy-THC

11-Nor-9-carboxy-THC (pronounced as "eleven-nor-nine-carboxy-T-H-C"), also known as THC-COOH, is a secondary metabolite of THC, the primary psychoactive compound found in cannabis.

Etymology

The term "11-Nor-9-carboxy-THC" is derived from the chemical structure of the compound. The "11-Nor" refers to the absence of a carbon atom at the 11th position in the molecule, and the "9-carboxy" refers to the presence of a carboxyl group at the 9th position. The "THC" in the name stands for Tetrahydrocannabinol, the parent compound from which 11-Nor-9-carboxy-THC is metabolized.

Metabolism

When THC is consumed, it is metabolized in the liver by the enzyme cytochrome P450. One of the primary metabolites produced is 11-Nor-9-carboxy-THC. This metabolite is not psychoactive, meaning it does not produce the "high" associated with THC. However, it is often detected in urine drug tests as a marker for recent cannabis use.

Detection

11-Nor-9-carboxy-THC is the primary metabolite detected in urine drug tests for cannabis. It can be detected for a longer period of time after cannabis use than THC itself, making it a more reliable marker for recent use. The detection window can vary depending on the frequency and quantity of cannabis use, as well as individual metabolic factors.

Related Terms

  • THC: The primary psychoactive compound in cannabis, from which 11-Nor-9-carboxy-THC is metabolized.
  • Cannabis: The plant species that produces THC.
  • Cytochrome P450: The enzyme that metabolizes THC into 11-Nor-9-carboxy-THC.
  • Drug test: A test that can detect the presence of 11-Nor-9-carboxy-THC in urine.

External links

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