Appetite suppressant medications

Appetite suppressants, also termed anorexiants or anorectics, are medications designed to curb hunger and reduce the urge to consume food, thus assisting individuals in achieving their weight loss goals. Given the global concern of obesity and its associated health risks, these drugs have garnered significant attention in recent decades.

Mechanism of Action

• Neurotransmitter Influence: Appetite suppressants primarily function by affecting certain neurotransmitters in the brain that regulate mood and appetite. By modulating these neurotransmitters, the drugs can reduce feelings of hunger.
• Hormonal Interplay: Some appetite suppressants influence hunger-related hormones, helping to create a sensation of fullness or satiety.

Types of Appetite Suppressants

There are various appetite suppressants approved for use, each with its unique properties:

• Phentermine: Often prescribed for short-term weight management in conjunction with diet and exercise.
• Orlistat (Alli): Functions by inhibiting fat absorption in the intestines.
• Lorcaserin (Belviq) (withdrawn): Works by activating a specific serotonin receptor in the brain associated with appetite control.
• Natural Suppressants: Including green tea extract and fiber supplements which may help to reduce appetite by promoting feelings of fullness.

Potential Side Effects

As with most medications, appetite suppressants come with their set of potential side effects:

• Cardiovascular: Elevated blood pressure and increased heart rate.
• Gastrointestinal: Nausea, constipation, and potential liver damage (in the case of Orlistat).
• Neurological: Dizziness, headache, and potential mood alterations.
• Endocrine: Changes in glucose metabolism leading to hyperglycemia.

It is pivotal to consult a healthcare provider before initiating any appetite suppressant to fully understand the risks and benefits.

Usage and Guidelines

• Prescription-Based: Some appetite suppressants are available only with a doctor's prescription, especially those with potential for severe side effects or abuse.
• Over-the-Counter: Few suppressants are available OTC, but it's essential to be informed and cautious about their efficacy and safety.
• Duration: These drugs are typically recommended for short-term use unless prescribed otherwise by a medical professional.
• Conjunction with Lifestyle Changes: For optimal results, appetite suppressants should be combined with a balanced diet and regular physical activity.

List of anorectic medications

• Acridorex
• Adderall
• Amfecloral
• Amfepentorex
• Amfepramone
• Aminorex
• Amphetamine
• Benfluorex
• Benzphetamine
• Bupropion
• Bupropion/zonisamide
• Chlorosibutramine
• Chlorosipentramine
• Chlorphentermine
• Ciclazindol
• Clobenzorex
• Cloforex
• Clortermine
• Cocaine
• Desmethylsibutramine
• Dextroamphetamine
• Didesmethylsibutramine
• Difemetorex
• Drinabant
• E-6801
• E-6837
• Etilamfetamine
• Etolorex
• Exenatide
• Fenbutrazate
• Fenfluramine
• Fenfluramine/phentermine
• Fenisorex
• Flucetorex
• Flumexadol
• Fluoxetine
• Formetorex
• Furfenorex
• GW-803430
• Indanorex
• Khat
• Levophacetoperane
• Levopropylhexedrine
• Lisdexamfetamine
• Lorcaserin
• Methamphetamine
• Methastyridone
• 4-Methylamphetamine
• Morforex
• Naltrexone/bupropion
• NGD-4715
• Nicotine
• Norfenfluramine
• Norpropylhexedrine
• Oxifentorex
• Oxyntomodulin
• P57 (glycoside)
• PDM-35
• Pentorex
• Phendimetrazine
• Phenmetrazine
• Phentermine
• Phentermine/topiramate
• 2-Phenyl-3-aminobutane
• Phenylpropanolamine
• Picilorex
• Propylhexedrine
• Rimonabant
• Rosonabant
• Setazindol
• Setmelanotide
• Sibutramine
• Simmondsin
• SNAP-94847
• Substituted phenylmorpholine
• Taranabant
• Tesofensine
• Tiflorex
• TM-38837
• WAY-629
• WAY-161503
• Xylopropamine

Also see

• Weight loss pills
• Glossary of anorectics

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