Pyrovalerone
Pyrovalerone
Pyrovalerone (pronounced: py-roh-va-leh-rone) is a psychoactive drug with stimulant effects. It is chemically related to other drugs of the amphetamine family and is used in the treatment of chronic fatigue and as an appetite suppressant.
Etymology
The term "Pyrovalerone" is derived from the Greek words "pyr" meaning fire, "valer" meaning strength, and "one" indicating it is a chemical compound. It was first synthesized in the 1960s.
Pharmacology
Pyrovalerone acts primarily as a norepinephrine-dopamine reuptake inhibitor (NDRI), increasing the levels of the norepinephrine and dopamine neurotransmitters in the brain by inhibiting their reuptake into neurons. This leads to increased neuronal activity, which is thought to result in increased alertness, attention, and energy.
Medical Uses
Pyrovalerone is used in the treatment of chronic fatigue syndrome (CFS) and as an appetite suppressant in the treatment of obesity. It is also used off-label for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
Side Effects
Common side effects of pyrovalerone include restlessness, insomnia, and increased heart rate. More serious side effects can include hallucinations, paranoia, and severe cardiac effects.
Related Terms
- Amphetamine
- Norepinephrine-dopamine reuptake inhibitor
- Chronic fatigue syndrome
- Obesity
- Attention deficit hyperactivity disorder
- Narcolepsy
External links
- Medical encyclopedia article on Pyrovalerone
- Wikipedia's article - Pyrovalerone
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