Fenbutrazate

Stimulant drug

Fenbutrazate
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Fenbutrazate is a stimulant drug that was developed in the 1960s. It is chemically related to phenethylamine and is known for its effects on the central nervous system. Fenbutrazate is primarily used as an anorectic agent, meaning it is used to suppress appetite.

Chemical Structure and Properties

Chemical structure of Fenbutrazate

Fenbutrazate is an ester of ethyl 3-phenyl-2-(p-tolyl)butanoate. Its chemical structure includes a phenyl group and a p-tolyl group, which contribute to its pharmacological activity. The presence of these aromatic rings is typical of many stimulant drugs, which often interact with neurotransmitter systems in the brain.

Pharmacology

Fenbutrazate acts as a central nervous system stimulant. It is believed to exert its effects by increasing the levels of certain neurotransmitters, such as dopamine and norepinephrine, in the brain. This increase in neurotransmitter levels leads to enhanced alertness, reduced fatigue, and appetite suppression.

Medical Uses

Fenbutrazate has been used primarily as an anorectic agent. It is prescribed to aid in weight loss by reducing appetite. The drug is typically used in conjunction with a calorie-restricted diet and exercise program. However, due to the potential for abuse and side effects, its use is limited and it is not widely available in many countries.

Side Effects

As with other stimulant drugs, fenbutrazate can cause a range of side effects. Common side effects include increased heart rate, elevated blood pressure, insomnia, and anxiety. Long-term use can lead to dependence and withdrawal symptoms upon cessation.

Legal Status

The legal status of fenbutrazate varies by country. In some regions, it is classified as a controlled substance due to its potential for abuse and addiction. In others, it may be available by prescription for specific medical conditions.

Related Compounds

Fenbutrazate is chemically related to other stimulant drugs such as amphetamine and methylphenidate. These compounds share similar mechanisms of action and are used for similar therapeutic purposes, although they differ in potency and side effect profiles.

See Also

• Stimulant
• Anorectic
• Phenethylamine
• Amphetamine

Related Pages

• Central nervous system
• Neurotransmitter
• Dopamine
• Norepinephrine