Mazindol
Mazindol
Mazindol (pronounced: ma-zin-dol) is a stimulant drug of the tetracyclic chemical class that is used in the treatment of obesity. It was developed by the Swiss pharmaceutical company Sandoz in the 1970s.
Etymology
The term "Mazindol" is derived from the chemical name of the drug, which is 5-(4-Chlorophenyl)-5-hydroxy-2,5-dihydro-1H-imidazo[2,1-a]isoindol-5-ol.
Usage
Mazindol is primarily used as an anorectic or appetite suppressant in the treatment of exogenous obesity. It is typically prescribed for individuals who have not been able to lose weight through diet and exercise alone.
Mechanism of Action
Mazindol works by inhibiting the reuptake of norepinephrine, dopamine, and serotonin in the brain. This leads to an increase in the levels of these neurotransmitters in the synaptic cleft, which in turn suppresses appetite.
Side Effects
Common side effects of Mazindol include dry mouth, constipation, insomnia, and increased heart rate. More serious side effects can include high blood pressure, heart palpitations, and psychological dependence.
Related Terms
External links
- Medical encyclopedia article on Mazindol
- Wikipedia's article - Mazindol
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