Klüver–Bucy syndrome

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Syndrome resulting from bilateral lesions of the medial temporal lobe


Klüver-Bucy syndrome
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In Klüver–Bucy syndrome, a patient will display placidity, hyperorality, hypersexuality, and hyperphagia.

Other Names

Bilateral temporal lobe disorder; Post-encephalitic Kluver Bucy syndrome (type); Post-traumatic Kluver Bucy syndrome (type); Memory loss, extreme sexual behavior, placidity, and visual distractibility

Cause

This condition results from bilateral destruction of the amygdaloid bodies of the limbic system.

Clinical features

Kluver Bucy is a rare behavioral impairment characterized by inappropriate sexual behaviors and mouthing of objects. Other signs and symptoms, include a diminished ability to visually recognize objects, loss of normal fear and anger responses, memory loss, distractibility etc.

Associated conditions

It is associated with damage to the anterior temporal lobes of the brain. Cases have been reported in association with herpes encephalitis and head trauma.

Treatment

Treatment is symptomatic and may include the use of psychotropic medications.[2]

Also see

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NIH genetic and rare disease info

Klüver–Bucy syndrome is a rare disease.


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Contributors: Prab R. Tumpati, MD