Inclusion body myositis

Inclusion Body Myositis (IBM) (pronunciation: in-kloo-zhun bod-ee my-uh-sahy-tis) is a progressive muscle disorder characterized by muscle inflammation, weakness, and atrophy (wasting). It is a type of inflammatory myopathy.

Etymology

The term "Inclusion Body Myositis" is derived from the characteristic 'inclusions' or abnormal clusters of proteins seen in muscle fibers and 'myositis' which means inflammation of the muscles.

Symptoms

The symptoms of IBM usually progress slowly over months or years. The most common symptoms include:

• Progressive weakness of the muscles of the wrists and fingers
• Difficulty swallowing
• Falling and tripping due to weakness of the leg muscles
• Muscle wasting in the forearms and thighs

Causes

The exact cause of IBM is unknown. It is thought to be due to a combination of genetic and environmental factors. Some researchers believe it may be an autoimmune disorder, where the body's immune system attacks its own tissues.

Diagnosis

Diagnosis of IBM is based on the patient's symptoms, a physical examination, and certain tests. These tests may include a muscle biopsy, which can show the characteristic 'inclusions' in the muscle fibers.

Treatment

There is currently no cure for IBM. Treatment is aimed at managing symptoms and improving quality of life. This may include physical therapy, occupational therapy, and speech therapy.

Related Terms

• Myopathy
• Muscle biopsy
• Autoimmune disorder
• Inflammatory myopathy

External links

• Medical encyclopedia article on Inclusion body myositis
• Wikipedia's article - Inclusion body myositis

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