CREST syndrome
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CREST Syndrome
CREST syndrome (pronounced: /krɛst sɪndroʊm/), also known as Calcinosis, Raynaud's phenomenon, Esophageal dysmotility, Sclerodactyly, and Telangiectasia syndrome, is a subtype of systemic scleroderma, a rheumatic and connective tissue disorder.
Etymology
The term "CREST" is an acronym derived from the major features of the syndrome:
- Calcinosis - The formation of calcium deposits in the connective tissues, which can be detected by X-ray.
- Raynaud's phenomenon - Spasms of the small arteries of the fingers and toes, often triggered by cold temperatures or emotional stress.
- Esophageal dysmotility - Impairment of the esophagus that can lead to difficulty swallowing.
- Sclerodactyly - Thickening and tightening of the skin on the fingers and hands, causing them to curl.
- Telangiectasia - Small red spots on the hands and face that are caused by the dilation of tiny blood vessels.
Related Terms
- Systemic sclerosis - A systemic autoimmune disease characterized by thickening of the skin caused by accumulation of collagen.
- Rheumatic disease - Diseases that affect the joints, muscles and soft tissues.
- Connective tissue disease - Diseases that affect the parts of the body that connect the structures of the body together.
- Autoimmune disease - Diseases in which the body's immune system attacks healthy cells.
See Also
External links
- Medical encyclopedia article on CREST syndrome
- Wikipedia's article - CREST syndrome
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