Dermatopolymyositis

From WikiMD's medical encyclopedia


Dermatopolymyositis
Synonyms Dermatomyositis, Polymyositis
Pronounce N/A
Specialty N/A
Symptoms Muscle weakness, Skin rash, Fatigue, Joint pain
Complications Interstitial lung disease, Cardiomyopathy, Dysphagia, Calcinosis
Onset Adulthood or Childhood
Duration Chronic
Types N/A
Causes Autoimmune disease, Genetic predisposition
Risks Family history, Infections, Environmental factors
Diagnosis Clinical examination, Muscle biopsy, Blood tests (e.g., Creatine kinase), Electromyography
Differential diagnosis Lupus erythematosus, Scleroderma, Polymyalgia rheumatica
Prevention N/A
Treatment Corticosteroids, Immunosuppressants, Physical therapy, Intravenous immunoglobulin
Medication N/A
Prognosis Variable; depends on severity and response to treatment
Frequency Rare
Deaths N/A


Dermatopolymyositis is a rare inflammatory disease marked by muscle weakness and a distinctive skin rash. It is an autoimmune disorder, which occurs when the body's immune system mistakenly attacks its own body tissues.

Symptoms

The most common symptoms of dermatopolymyositis include:

  • Muscle weakness, typically affecting muscles closest to the trunk, such as those in your hips, thighs, shoulders, upper arms and neck.
  • Skin rash, which often appears before muscle weakness. The rash looks patchy, with purple or red discolorations, and characteristically develops on the eyelids and on muscles used to control the neck, shoulders and hips.
  • Difficulty swallowing (Dysphagia)
  • Lung problems
  • Arthritis
  • Fatigue
  • Fever

Causes

The exact cause of dermatopolymyositis is unknown, but the disease has similarities to autoimmune disorders, in which the immune system mistakenly attacks the body's own tissues.

Diagnosis

Diagnosis of dermatopolymyositis is based on a physical examination, medical history, and certain diagnostic tests. These tests may include:

Treatment

Treatment for dermatopolymyositis is aimed at controlling the skin rash and improving muscle strength and function. Options include:

Prognosis

The prognosis for individuals with dermatopolymyositis varies. Some people experience a mild, self-limited disease while others have a chronic illness with progressive disability.

See also

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Contributors: Prab R. Tumpati, MD