Triclabendazole

Triclabendazole (pronounced trik-la-ben-da-zole) is a medication primarily used to treat liver fluke infections. It is a member of the benzimidazole family of anthelmintic drugs.

Etymology

The term "Triclabendazole" is derived from its chemical structure. The prefix "tri-" refers to the three chlorine (Cl) atoms, "ben-" refers to the benzene ring, and "-azole" is a common suffix for benzimidazole compounds.

Usage

Triclabendazole is used to treat infections caused by the liver fluke, Fasciola hepatica, and other species of the Fasciola genus. It is effective against both adult and immature flukes. The drug works by inhibiting the fluke's tubulin polymerisation, which is essential for its survival.

Side Effects

Common side effects of Triclabendazole include abdominal pain, nausea, headache, dizziness, and rash. In rare cases, it can cause serious liver problems.

Related Terms

Anthelmintic: A type of drug used to expel parasitic worms (helminths) from the body.
Benzimidazole: A type of organic compound that is used in many drugs, including Triclabendazole.
Fasciola hepatica: A parasitic liver fluke that is the primary target of Triclabendazole treatment.
Tubulin: A protein that is essential for the survival of many parasites, including the liver fluke.

External links

Medical encyclopedia article on Triclabendazole
Wikipedia's article - Triclabendazole

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Triclabendazole