Butyrophenone
Butyrophenone
Butyrophenone (pronunciation: byoo-tuh-roh-feh-none) is a class of pharmaceutical drugs primarily used in the treatment of various psychiatric disorders.
Etymology
The term "Butyrophenone" is derived from the chemical structure of these compounds, which consist of a butyrophenyl group attached to a central carbon atom.
Definition
Butyrophenones are a class of psychoactive drugs that act as antipsychotics. They are primarily used to treat schizophrenia, acute psychosis, and severe nausea and vomiting. The most well-known drug in this class is haloperidol, which is commonly used in the treatment of chronic psychiatric disorders.
Mechanism of Action
Butyrophenones work by blocking dopamine receptors in the brain, specifically the D2 receptor. This reduces the effect of dopamine, a neurotransmitter that plays a key role in mood, motivation, and reward. By blocking these receptors, butyrophenones can help to reduce symptoms of psychosis and improve mental clarity.
Related Terms
- Haloperidol: A butyrophenone antipsychotic used to treat a variety of psychiatric disorders.
- Droperidol: A butyrophenone used in anesthesia for its antiemetic (anti-nausea) and sedative properties.
- Antipsychotic: A class of drugs used to manage psychosis, particularly in schizophrenia and bipolar disorder.
- Dopamine: A neurotransmitter that plays several important roles in the brain and body.
- D2 receptor: A type of dopamine receptor that butyrophenones act upon.
See Also
External links
- Medical encyclopedia article on Butyrophenone
- Wikipedia's article - Butyrophenone
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