Quinoline

Quinoline is a heterocyclic aromatic organic compound with the chemical formula C9H7N. It is a colorless hygroscopic liquid with a strong odor. Aged samples, if exposed to light, become yellow and later brown. Quinoline is only slightly soluble in cold water but dissolves readily in hot water and most organic solvents. Quinoline is mainly used as a precursor to other specialty chemicals, which range from dyes to pharmaceuticals.

History

Quinoline was first extracted from coal tar in 1834 by Friedrich Runge. He named it leucol. In 1842, Charles Gerhardt obtained a compound by dry distillation of quinic acid. He named this compound quinoline to denote a new type of aromatic compound.

Production

Quinoline is produced from coal tar and from anthracene. It is also a byproduct of the production of acetylene.

Uses

Quinoline is used as a solvent for resins and terpenes. It is also used as a denaturant for alcohol and in the manufacture of dyes, pharmaceuticals, and disinfectants.

Health effects

Quinoline is harmful if swallowed. It causes skin and serious eye irritation. It may cause respiratory irritation and may be harmful if inhaled. It is very toxic to aquatic life with long lasting effects.

See also

• Isoquinoline
• Pyridine
• Naphthalene

References

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