Serotonin receptor antagonist
Serotonin Receptor Antagonist
A Serotonin Receptor Antagonist (pronunciation: sɛrəˈtoʊnɪn rɪˈsɛptər æntəˈɡɒnɪst) is a type of drug that inhibits the action of serotonin in the brain by blocking the serotonin receptors.
Etymology
The term "Serotonin Receptor Antagonist" is derived from the neurotransmitter serotonin, and the term antagonist, which in pharmacology refers to a substance that interferes with or inhibits the physiological action of another.
Function
Serotonin receptor antagonists are primarily used in the treatment of nausea and vomiting, as well as irritable bowel syndrome and other gastrointestinal disorders. They can also be used in the treatment of schizophrenia and depression.
Types
There are several types of serotonin receptor antagonists, including:
- 5-HT3 antagonists: These are used primarily to treat nausea and vomiting caused by chemotherapy, radiation therapy, or surgery.
- 5-HT2A antagonists: These are used in the treatment of insomnia, anxiety, and depression.
- 5-HT2C antagonists: These are used in the treatment of obesity, schizophrenia, and depression.
Related Terms
- Serotonin: A neurotransmitter that transmits signals in the brain.
- Antagonist: A substance that interferes with or inhibits the physiological action of another.
- Neurotransmitter: A substance that transmits nerve impulses across a synapse.
- 5-HT3 antagonist: A type of serotonin receptor antagonist used to treat nausea and vomiting.
- 5-HT2A antagonist: A type of serotonin receptor antagonist used to treat insomnia, anxiety, and depression.
- 5-HT2C antagonist: A type of serotonin receptor antagonist used to treat obesity, schizophrenia, and depression.
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