Esmolol

Esmolol

Esmolol (pronounced es-MOH-lol) is a cardioselective beta1 receptor blocker with rapid onset, a very short duration of action, and no significant intrinsic sympathomimetic activity. It is a class II antiarrhythmic.

Etymology

The term "Esmolol" is derived from the chemical structure of the drug, specifically the presence of an ester group (Es-) and a phenol group (-molol). The "-olol" suffix is common in many beta blockers, indicating their function.

Pharmacology

Esmolol works by blocking the action of certain natural chemicals in your body, such as epinephrine, on the heart and blood vessels. This effect reduces heart rate, blood pressure, and strain on the heart.

Indications

Esmolol is used to control rapid heartbeats or abnormal heart rhythms. This includes postoperative tachycardia and/or hypertension, tachyarrhythmias, and the short-term treatment of tachycardia and/or hypertension in the emergency department.

Contraindications

Esmolol should not be used in people with cardiogenic shock, uncontrolled heart failure, sick sinus syndrome, or second and third degree heart block unless a functioning pacemaker is present.

Side Effects

Common side effects of Esmolol include dizziness, weakness, and nausea. Serious side effects may include slow heart rate, severe allergic reactions, and bronchospasm.

Related Terms

• Beta Blocker
• Cardioselective
• Epinephrine
• Tachycardia
• Hypertension
• Heart Block
• Cardiogenic Shock
• Heart Failure

External links

• Medical encyclopedia article on Esmolol
• Wikipedia's article - Esmolol

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