Rhabdomyoma: Difference between revisions
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[[File:Fetal intermediate cellular type rhabdomyoma.JPG|thumb|Photomicrograph of fetal-type rhabdomyoma: Note the plump, pink benign skeletal muscle cells.]] | {{Infobox medical condition | ||
| name = Rhabdomyoma | |||
| image = [[File:Cardiac_rhabdomyoma.jpg|left|thumb|Cardiac rhabdomyoma]] | |||
| caption = Cardiac rhabdomyoma | |||
| field = [[Oncology]], [[Pathology]] | |||
| synonyms = | |||
| symptoms = Often asymptomatic, may cause [[arrhythmia]], [[heart failure]] | |||
| complications = | |||
| onset = | |||
| duration = | |||
| types = [[Cardiac rhabdomyoma]], [[Fetal rhabdomyoma]], [[Adult rhabdomyoma]] | |||
| causes = | |||
| risks = | |||
| diagnosis = [[Histopathology]], [[Imaging studies]] | |||
| differential = [[Rhabdomyosarcoma]], [[Fibroma]], [[Myxoma]] | |||
| prevention = | |||
| treatment = Often none required, surgical removal if symptomatic | |||
| medication = | |||
| prognosis = Generally good, may regress spontaneously | |||
| frequency = Rare | |||
}} | |||
[[File:Fetal intermediate cellular type rhabdomyoma.JPG|left|thumb|Photomicrograph of fetal-type rhabdomyoma: Note the plump, pink benign skeletal muscle cells.]] | |||
A '''rhabdomyoma''' is a [[benign tumor]] that originates from [[striated muscle]]. These tumors can be categorized based on their location: either "cardiac" (within the heart) or "extracardiac" (outside the heart). Rhabdomyomas play a significant role in pediatric and adult oncology due to their associations with various conditions and potential complications. | A '''rhabdomyoma''' is a [[benign tumor]] that originates from [[striated muscle]]. These tumors can be categorized based on their location: either "cardiac" (within the heart) or "extracardiac" (outside the heart). Rhabdomyomas play a significant role in pediatric and adult oncology due to their associations with various conditions and potential complications. | ||
=== Classification === | === Classification === | ||
Rhabdomyomas are classified based on their occurrence location. The main categories include: | Rhabdomyomas are classified based on their occurrence location. The main categories include: | ||
* '''Cardiac rhabdomyomas:''' These are the most prevalent primary tumors of the heart in infants and children. | * '''Cardiac rhabdomyomas:''' These are the most prevalent primary tumors of the heart in infants and children. | ||
* '''Extracardiac rhabdomyomas:''' These manifest outside the heart and can be further subdivided into: | * '''Extracardiac rhabdomyomas:''' These manifest outside the heart and can be further subdivided into: | ||
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** '''Fetal type''' | ** '''Fetal type''' | ||
** '''Genital type''' | ** '''Genital type''' | ||
=== Associations and Manifestations === | === Associations and Manifestations === | ||
Cardiac rhabdomyomas have a known link with '''tuberous sclerosis''', a genetic disorder that affects multiple systems. In individuals diagnosed with tuberous sclerosis, rhabdomyomas might either regress and vanish entirely or maintain a consistent size without significant growth. | Cardiac rhabdomyomas have a known link with '''tuberous sclerosis''', a genetic disorder that affects multiple systems. In individuals diagnosed with tuberous sclerosis, rhabdomyomas might either regress and vanish entirely or maintain a consistent size without significant growth. | ||
While rhabdomyomas are chiefly associated with the heart and tongue, they can also develop in other parts of the body, such as the [[vagina]]. | While rhabdomyomas are chiefly associated with the heart and tongue, they can also develop in other parts of the body, such as the [[vagina]]. | ||
=== Malignant Potential === | === Malignant Potential === | ||
Malignant tumors arising from skeletal muscle are termed '''rhabdomyosarcoma'''. It is crucial to differentiate between benign rhabdomyomas and malignant rhabdomyosarcomas. Only in rare instances has malignant transformation been observed in fetal rhabdomyomas. When diagnosing rhabdomyomas in the tongue, another differential diagnosis to consider is the '''ectomesenchymal chondromyxoid tumor'''. | Malignant tumors arising from skeletal muscle are termed '''rhabdomyosarcoma'''. It is crucial to differentiate between benign rhabdomyomas and malignant rhabdomyosarcomas. Only in rare instances has malignant transformation been observed in fetal rhabdomyomas. When diagnosing rhabdomyomas in the tongue, another differential diagnosis to consider is the '''ectomesenchymal chondromyxoid tumor'''. | ||
=== Conclusion === | === Conclusion === | ||
Rhabdomyomas are benign muscle tumors that can have significant clinical implications, especially in pediatric populations. Proper diagnosis and differentiation from malignant counterparts are vital for appropriate management and prognosis. | Rhabdomyomas are benign muscle tumors that can have significant clinical implications, especially in pediatric populations. Proper diagnosis and differentiation from malignant counterparts are vital for appropriate management and prognosis. | ||
Revision as of 20:45, 8 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Rhabdomyoma | |
|---|---|
 | |
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Often asymptomatic, may cause arrhythmia, heart failure |
| Complications | |
| Onset | |
| Duration | |
| Types | Cardiac rhabdomyoma, Fetal rhabdomyoma, Adult rhabdomyoma |
| Causes | |
| Risks | |
| Diagnosis | Histopathology, Imaging studies |
| Differential diagnosis | Rhabdomyosarcoma, Fibroma, Myxoma |
| Prevention | |
| Treatment | Often none required, surgical removal if symptomatic |
| Medication | |
| Prognosis | Generally good, may regress spontaneously |
| Frequency | Rare |
| Deaths | N/A |
A rhabdomyoma is a benign tumor that originates from striated muscle. These tumors can be categorized based on their location: either "cardiac" (within the heart) or "extracardiac" (outside the heart). Rhabdomyomas play a significant role in pediatric and adult oncology due to their associations with various conditions and potential complications.
Classification
Rhabdomyomas are classified based on their occurrence location. The main categories include:
- Cardiac rhabdomyomas: These are the most prevalent primary tumors of the heart in infants and children.
- Extracardiac rhabdomyomas: These manifest outside the heart and can be further subdivided into:
- Adult type
- Fetal type
- Genital type
Associations and Manifestations
Cardiac rhabdomyomas have a known link with tuberous sclerosis, a genetic disorder that affects multiple systems. In individuals diagnosed with tuberous sclerosis, rhabdomyomas might either regress and vanish entirely or maintain a consistent size without significant growth. While rhabdomyomas are chiefly associated with the heart and tongue, they can also develop in other parts of the body, such as the vagina.
Malignant Potential
Malignant tumors arising from skeletal muscle are termed rhabdomyosarcoma. It is crucial to differentiate between benign rhabdomyomas and malignant rhabdomyosarcomas. Only in rare instances has malignant transformation been observed in fetal rhabdomyomas. When diagnosing rhabdomyomas in the tongue, another differential diagnosis to consider is the ectomesenchymal chondromyxoid tumor.
Conclusion
Rhabdomyomas are benign muscle tumors that can have significant clinical implications, especially in pediatric populations. Proper diagnosis and differentiation from malignant counterparts are vital for appropriate management and prognosis.
External links
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| Cancers from and involving the heart | ||||
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| Tumors of lip, oral cavity and pharynx / head and neck cancer | ||||||||||||||||
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