Hibernoma

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Hibernoma
Synonyms
Pronounce	N/A
Specialty	N/A
Symptoms	Usually asymptomatic, may present as a painless mass
Complications	Rarely, compression of adjacent structures
Onset	Typically in adults
Duration	Indefinite
Types	N/A
Causes	Unknown
Risks
Diagnosis	Histopathology, Imaging studies
Differential diagnosis	Liposarcoma, Lipoma, Myxoid liposarcoma
Prevention	None
Treatment	Surgical excision
Medication	None
Prognosis	Excellent with complete excision
Frequency	Rare
Deaths	N/A

Hibernoma

Hibernoma is a rare, benign tumor that originates from brown fat tissue. The name "hibernoma" is derived from the tumor's resemblance to the brown fat found in hibernating animals.

History

The first known case of hibernoma was reported by Merkel in 1906. Since then, fewer than 200 cases have been reported in the medical literature.

Pathology

Hibernomas are composed of brown fat cells, which are larger than white fat cells and contain more mitochondria. These cells are responsible for heat production in the body, a process known as thermogenesis.

Clinical Presentation

Patients with hibernoma often present with a slow-growing, painless mass. The most common locations for hibernomas are the thigh, shoulder, back, and neck.

Diagnosis

The diagnosis of hibernoma is typically made through a combination of imaging studies and biopsy. On imaging, hibernomas appear as well-defined, vascular masses. The definitive diagnosis is made by biopsy, which shows the characteristic brown fat cells.

Treatment

The treatment for hibernoma is surgical removal. Because hibernomas are benign, they do not spread to other parts of the body, and complete removal is usually curative.

Prognosis

The prognosis for patients with hibernoma is excellent. After surgical removal, the recurrence rate is very low.

See Also

• Lipoma
• Liposarcoma
• Benign tumors