Histiocytoma
| Histiocytoma | |
|---|---|
| Synonyms | Dermatofibroma, Fibrous histiocytoma |
| Pronounce | N/A |
| Specialty | Dermatology |
| Symptoms | Firm, raised skin nodule |
| Complications | N/A |
| Onset | Any age, most common in adults |
| Duration | Persistent |
| Types | N/A |
| Causes | Unknown, possibly trauma or insect bite |
| Risks | More common in women |
| Diagnosis | Clinical examination, biopsy |
| Differential diagnosis | Dermatofibrosarcoma protuberans, melanoma, basal cell carcinoma |
| Prevention | N/A |
| Treatment | Observation, surgical excision if symptomatic |
| Medication | N/A |
| Prognosis | Excellent, benign condition |
| Frequency | Common |
| Deaths | N/A |
Histiocytoma is a type of tumor that originates from the histiocyte cells. Histiocytes are a type of immune cell that are part of the body's immune system. They are found in many tissues of the body, including the skin, lung, and bone marrow. Histiocytomas can occur in both adults and children, and can affect various parts of the body.
Types of Histiocytoma
There are several types of histiocytomas, including:
- Langerhans cell histiocytosis (LCH): This is the most common type of histiocytoma. It can affect any age group, but is most common in children. LCH can affect various parts of the body, including the skin, bones, and lungs.
- Non-Langerhans cell histiocytosis (non-LCH): This type of histiocytoma is less common than LCH. It can also affect various parts of the body, but is more likely to affect the skin and lungs.
- Malignant histiocytoma: This is a rare type of histiocytoma that is cancerous. It can spread to other parts of the body and is often difficult to treat.
Symptoms
The symptoms of histiocytoma can vary depending on the type of histiocytoma and the part of the body that is affected. Common symptoms can include:
Diagnosis
Diagnosis of histiocytoma typically involves a biopsy of the affected tissue. The tissue sample is then examined under a microscope to look for the presence of histiocytes. Other tests, such as blood tests, imaging tests, and bone marrow biopsy, may also be used to help confirm the diagnosis and determine the extent of the disease.
Treatment
Treatment for histiocytoma depends on the type of histiocytoma and the extent of the disease. Treatment options can include:
- Surgery to remove the tumor
- Chemotherapy
- Radiation therapy
- Immunotherapy
Prognosis
The prognosis for histiocytoma can vary depending on the type of histiocytoma and the extent of the disease. Some types of histiocytoma, such as LCH, often have a good prognosis with treatment. However, malignant histiocytomas can be more difficult to treat and may have a poorer prognosis.
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Contributors: Prab R. Tumpati, MD