Fibromatosis

MEDICAL EDITOR

Prab R. Tumpati, MD — Editor-in-Chief, WikiMD Medical Encyclopedia
Internal medicine • Obesity medicine • Sleep medicine
Professional affiliations: Founder of WikiMD and W8MD Weight Loss, Sleep & MedSpa.
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Fibromatosis
Synonyms
Pronounce	N/A
Specialty	N/A
Symptoms	Lump, pain, swelling
Complications	Organ dysfunction, nerve compression
Onset	Any age, often 20-40 years
Duration	Chronic
Types	Desmoid tumor, superficial fibromatosis
Causes	Unknown, possibly genetic
Risks	Familial adenomatous polyposis, trauma
Diagnosis	Biopsy, imaging studies
Differential diagnosis	Sarcoma, lipoma, neurofibroma
Prevention	N/A
Treatment	Surgery, radiation therapy, chemotherapy
Medication	Nonsteroidal anti-inflammatory drugs, hormonal therapy
Prognosis	Variable, depends on type and location
Frequency	Rare
Deaths	N/A

Fibromatosis refers to a group of noncancerous tumors that can appear anywhere in the body. These tumors, also known as Desmoid tumors, are rare and can cause significant health problems. They are characterized by the overgrowth of fibrous tissue, which can lead to pain, limited movement, and other complications.

Causes

The exact cause of fibromatosis is unknown. However, it is believed to be related to genetic mutations. Some cases of fibromatosis are associated with certain inherited disorders, such as Gardner's syndrome and Familial adenomatous polyposis (FAP).

Symptoms

The symptoms of fibromatosis can vary depending on the location of the tumor. Common symptoms include:

• A noticeable lump or swelling
• Pain or discomfort
• Limited movement

In some cases, fibromatosis may not cause any symptoms and may only be discovered during a routine medical examination.

Diagnosis

Diagnosis of fibromatosis typically involves a physical examination, medical history, and imaging tests such as MRI or CT scan. A biopsy may also be performed to confirm the diagnosis.

Treatment

Treatment for fibromatosis depends on the size and location of the tumor, as well as the patient's overall health. Options may include:

• Surgery to remove the tumor
• Radiation therapy
• Chemotherapy
• Targeted therapy

Prognosis

The prognosis for fibromatosis varies. Some tumors may remain stable or even shrink without treatment, while others may grow rapidly and cause significant complications.

See also

• Soft tissue tumor
• Benign tumor
• Familial adenomatous polyposis
• Gardner's syndrome