Oral submucous fibrosis

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Oral Submucous Fibrosis (pronunciation: /ˈɔːrəl sʌbˈmjuːkəs faɪˈbrəʊsɪs/) is a chronic, complex, premalignant condition of the oral cavity and the oropharynx, characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues.

Etymology

The term "Oral Submucous Fibrosis" is derived from the Latin words "Oral" meaning mouth, "Sub" meaning under, "Mucous" referring to the slimy substance secreted by the mucous membranes, and "Fibrosis" meaning the thickening and scarring of connective tissue.

Symptoms

The symptoms of Oral Submucous Fibrosis include:

  • Inability to open mouth fully (trismus)
  • Burning sensation in mouth
  • Ulceration of the oral mucosa
  • Difficulty in eating and speaking

Causes

The exact cause of Oral Submucous Fibrosis is unknown, but it is associated with the chewing of areca nut (betel nut), which is a common habit in certain parts of Asia. Other factors such as nutritional deficiencies, immunologic processes, and genetic predisposition may also play a role.

Treatment

Treatment of Oral Submucous Fibrosis depends on the severity of the condition and may include:

  • Cessation of areca nut chewing
  • Medications such as corticosteroids and hyaluronidase
  • Physiotherapy
  • Surgical intervention in severe cases

Related Terms

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