Chondroid lipoma

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Chondroid Lipoma

Chondroid lipoma (pronunciation: kon-droid li-po-ma) is a rare benign lipomatous tumor that mimics a variety of soft tissue tumors. It was first described by Meis and Enzinger in 1993.

Etymology

The term "chondroid" is derived from the Greek word "chondros" meaning cartilage and "oid" meaning like. "Lipoma" is derived from the Greek word "lipos" meaning fat and "oma" meaning tumor. Thus, "chondroid lipoma" refers to a lipoma that resembles cartilage.

Clinical Presentation

Chondroid lipomas are typically found in the limbs and limb girdles, particularly in the thigh and shoulder regions. They are often mistaken for myxoid liposarcoma due to their similar appearance on imaging studies.

Histopathology

Histologically, chondroid lipomas are characterized by the presence of mature adipocytes, vacuolated lipoblast-like cells, and a chondromyxoid matrix. The tumor cells are often positive for S-100 protein, a marker for cells of neural crest origin.

Diagnosis

The diagnosis of chondroid lipoma is often made by a combination of clinical, radiological, and histopathological findings. Magnetic resonance imaging (MRI) can be particularly useful in differentiating chondroid lipomas from other soft tissue tumors.

Treatment

The treatment of choice for chondroid lipoma is surgical excision. Due to the benign nature of the tumor, recurrence after complete excision is rare.

Related Terms

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