Intravascular papillary endothelial hyperplasia: Difference between revisions
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{{Infobox medical condition | |||
| name = Intravascular papillary endothelial hyperplasia | |||
| image = [[File:Intravascular_papillary_endothelial_hyperplasia_--_very_low_mag.jpg|alt=Micrograph of intravascular papillary endothelial hyperplasia]] | |||
| caption = Micrograph of intravascular papillary endothelial hyperplasia | |||
| field = [[Pathology]] | |||
| synonyms = Masson's tumor, Masson's hemangioma | |||
| symptoms = [[Nodule]], [[mass (lump)]], [[pain]] | |||
| complications = Rarely [[thrombosis]] | |||
| onset = Any age, most common in adults | |||
| duration = Chronic | |||
| causes = [[Vascular]] [[trauma]], [[thrombosis]] | |||
| risks = [[Vascular malformations]], [[hemangiomas]] | |||
| diagnosis = [[Histopathology]] | |||
| differential = [[Angiosarcoma]], [[Kaposi's sarcoma]], [[Hemangioma]] | |||
| treatment = [[Surgical excision]] | |||
| prognosis = Excellent with complete excision | |||
| frequency = Rare | |||
}} | |||
'''Intravascular papillary endothelial hyperplasia''' (IPEH), also known as '''Masson's tumor''', is a benign vascular lesion characterized by excessive proliferation of endothelial cells. It is a rare condition that can occur anywhere in the body, but is most commonly found in the skin and subcutaneous tissues. | '''Intravascular papillary endothelial hyperplasia''' (IPEH), also known as '''Masson's tumor''', is a benign vascular lesion characterized by excessive proliferation of endothelial cells. It is a rare condition that can occur anywhere in the body, but is most commonly found in the skin and subcutaneous tissues. | ||
==Etiology== | ==Etiology== | ||
The exact cause of IPEH is unknown. However, it is believed to be a reactive process that occurs in response to vascular injury or thrombosis. Some studies suggest that it may be associated with certain conditions such as [[hemangioma]], [[venous malformation]], and [[pyogenic granuloma]]. | The exact cause of IPEH is unknown. However, it is believed to be a reactive process that occurs in response to vascular injury or thrombosis. Some studies suggest that it may be associated with certain conditions such as [[hemangioma]], [[venous malformation]], and [[pyogenic granuloma]]. | ||
==Clinical Presentation== | ==Clinical Presentation== | ||
Patients with IPEH typically present with a slow-growing, painless mass. The size of the lesion can vary, but it is usually less than 2 cm in diameter. The skin over the lesion may appear normal or may show signs of [[erythema]] or [[ulceration]]. In rare cases, patients may experience pain or tenderness. | Patients with IPEH typically present with a slow-growing, painless mass. The size of the lesion can vary, but it is usually less than 2 cm in diameter. The skin over the lesion may appear normal or may show signs of [[erythema]] or [[ulceration]]. In rare cases, patients may experience pain or tenderness. | ||
==Diagnosis== | ==Diagnosis== | ||
The diagnosis of IPEH is usually made based on histopathological examination. The lesion is characterized by the presence of papillary structures with a central [[hyaline]] core and an outer layer of proliferating endothelial cells. Immunohistochemical staining can be used to confirm the diagnosis. | The diagnosis of IPEH is usually made based on histopathological examination. The lesion is characterized by the presence of papillary structures with a central [[hyaline]] core and an outer layer of proliferating endothelial cells. Immunohistochemical staining can be used to confirm the diagnosis. | ||
|thumb|left]]==Treatment== | |||
==Treatment== | |||
The treatment of choice for IPEH is surgical excision. The prognosis is generally good, with a low risk of recurrence. | The treatment of choice for IPEH is surgical excision. The prognosis is generally good, with a low risk of recurrence. | ||
==See Also== | ==See Also== | ||
* [[Vascular lesion]] | * [[Vascular lesion]] | ||
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* [[Venous malformation]] | * [[Venous malformation]] | ||
* [[Pyogenic granuloma]] | * [[Pyogenic granuloma]] | ||
{{Soft tissue tumors and sarcomas}} | {{Soft tissue tumors and sarcomas}} | ||
{{Dermal-growth-stub}} | {{Dermal-growth-stub}} | ||
[[Category:Medical conditions]] | [[Category:Medical conditions]] | ||
[[Category:Vascular diseases]] | [[Category:Vascular diseases]] | ||
[[Category:Skin conditions]] | [[Category:Skin conditions]] | ||
Latest revision as of 10:15, 13 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
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| Intravascular papillary endothelial hyperplasia | |
|---|---|
| |
| Synonyms | Masson's tumor, Masson's hemangioma |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Nodule, mass (lump), pain |
| Complications | Rarely thrombosis |
| Onset | Any age, most common in adults |
| Duration | Chronic |
| Types | N/A |
| Causes | Vascular trauma, thrombosis |
| Risks | Vascular malformations, hemangiomas |
| Diagnosis | Histopathology |
| Differential diagnosis | Angiosarcoma, Kaposi's sarcoma, Hemangioma |
| Prevention | N/A |
| Treatment | Surgical excision |
| Medication | N/A |
| Prognosis | Excellent with complete excision |
| Frequency | Rare |
| Deaths | N/A |
Intravascular papillary endothelial hyperplasia (IPEH), also known as Masson's tumor, is a benign vascular lesion characterized by excessive proliferation of endothelial cells. It is a rare condition that can occur anywhere in the body, but is most commonly found in the skin and subcutaneous tissues.
Etiology[edit]
The exact cause of IPEH is unknown. However, it is believed to be a reactive process that occurs in response to vascular injury or thrombosis. Some studies suggest that it may be associated with certain conditions such as hemangioma, venous malformation, and pyogenic granuloma.
Clinical Presentation[edit]
Patients with IPEH typically present with a slow-growing, painless mass. The size of the lesion can vary, but it is usually less than 2 cm in diameter. The skin over the lesion may appear normal or may show signs of erythema or ulceration. In rare cases, patients may experience pain or tenderness.
Diagnosis[edit]
The diagnosis of IPEH is usually made based on histopathological examination. The lesion is characterized by the presence of papillary structures with a central hyaline core and an outer layer of proliferating endothelial cells. Immunohistochemical staining can be used to confirm the diagnosis. |thumb|left]]==Treatment== The treatment of choice for IPEH is surgical excision. The prognosis is generally good, with a low risk of recurrence.
See Also[edit]
