Vorapaxar
Vorapaxar
Vorapaxar (pronounced: vo-RA-pax-ar) is a medication used to reduce the risk of thrombotic cardiovascular events in patients with a history of myocardial infarction or with peripheral arterial disease.
Etymology
The name Vorapaxar is derived from the chemical structure of the drug. The prefix "Vora-" is derived from the Latin word "vorax", meaning "devouring", and the suffix "-paxar" is an arbitrary suffix used to denote its classification as a protease-activated receptor antagonist.
Pharmacology
Vorapaxar is a protease-activated receptor-1 (PAR-1) antagonist. It works by inhibiting the action of thrombin, a protein involved in blood clotting, on PAR-1 receptors. This prevents platelet aggregation, reducing the risk of thrombotic cardiovascular events.
Related Terms
- Thrombin
- Protease-activated receptor-1
- Platelet aggregation
- Myocardial infarction
- Peripheral arterial disease
See Also
External links
- Medical encyclopedia article on Vorapaxar
- Wikipedia's article - Vorapaxar
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