REG1
REG1 or Regenerating islet-derived protein 1 is a protein that in humans is encoded by the REG1A gene. It is a member of the Regenerating islet-derived gene family and encodes a protein that is secreted by the exocrine pancreas. It is highly similar to the islet of Langerhans regenerating protein.
Function
REG1 is involved in the growth and differentiation of cellular structures and has a role in regeneration and tissue repair. It is also associated with the immune response, as it has been found to have anti-inflammatory properties.
Clinical significance
In the medical field, REG1 is of interest due to its involvement in several diseases. It is overexpressed in some types of cancer, including pancreatic cancer and colorectal cancer. It is also associated with chronic pancreatitis and Type 2 diabetes.
Research
Research into REG1 is ongoing, with studies focusing on its role in disease progression and potential as a therapeutic target.
See also
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Contributors: Prab R. Tumpati, MD
