Factor Xa
Factor Xa
Factor Xa (pronounced as "factor ten-a") is an important enzyme (protease) in the blood coagulation cascade. It is formed from Factor X by the action of both Factor IXa and Factor VIIa.
Etymology
The term "Factor Xa" is derived from the Roman numeral for ten (X) and the lowercase "a" denotes the activated form of Factor X.
Function
Factor Xa plays a crucial role in the blood coagulation cascade, which is a complex process that leads to the formation of a blood clot. It catalyzes the conversion of prothrombin to thrombin, which in turn converts fibrinogen to fibrin, the main protein component of a blood clot.
Related Terms
- Factor X: The precursor to Factor Xa. It is activated by either Factor IXa (in the intrinsic pathway) or Factor VIIa (in the extrinsic pathway).
- Prothrombin: A protein present in blood plasma that is converted into active thrombin during coagulation.
- Thrombin: An enzyme in blood plasma that causes the clotting of blood by converting fibrinogen to fibrin.
- Fibrinogen: A protein in the blood plasma that is essential for the coagulation of blood. It is converted into fibrin by the action of thrombin.
- Fibrin: The final product of the blood coagulation cascade. It forms a fibrous mesh that impedes the flow of blood, thereby forming a clot.
External links
- Medical encyclopedia article on Factor Xa
- Wikipedia's article - Factor Xa
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