Template:Antimycobacterials

From WikiMD's Wellness Encyclopedia

Antimycobacterials, including tuberculosis treatment and leprostatic agents (J04)

Nucleic acid inhibitor

Rifamycins/ RNA polymerase inhibitor	* Rifampicin^# Rifabutin Rifapentine Rifalazil^§
Antifolates/DSI	* Dapsone^# Acedapsone Diucifon Promin Solasulfone Sulfoxone
ASA	* 4-Aminosalicylic acid^# (Calcium aminosalicylate Sodium aminosalicylate)
Topoisomerase inhibitors/ quinolones	* Gatifloxacin Moxifloxacin

Protein synthesis inhibitor

Aminoglycosides	* Amikacin^# Kanamycin Streptomycin^#
Oxazolidone	* Linezolid Sutezolid
Polypeptide antibiotics	* Capreomycin

Cell envelope antibiotic

Peptidoglycan layer	* Alanine analogue: Cycloserine^#
Arabinogalactan layer	* Ethylenediamine/arabinosyltransferase inhibitor: Ethambutol^# SQ109^†
Mycolic acid layer	* Hydrazides/mycolic acid synth. inhibition: Isoniazid^# Methaniazide Thiocarbamides: Ethionamide^# Prothionamide Thiocarlide Others/unsorted: Thioacetazone (amithiozone)

Other/unknown

* Phenazine (Clofazimine)^#

Pyrazine (Pyrazinamide^#, Morinamide)
Isoxazole (Terizidone)
Bedaquiline
Nitroimidazole (Delamanid, Pretomanid)

Combinations

* Ethambutol/isoniazid

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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