Agranulocytosis
Agranulocytosis
Agranulocytosis (pronounced: a-gran-yoo-lo-sy-toh-sis) is a serious medical condition characterized by a severe and dangerous lowering of certain types of white blood cells called granulocytes.
Etymology
The term "Agranulocytosis" is derived from the Greek words "a-" meaning "without", "granulo-" referring to granules, and "-cytosis" indicating an abnormal increase in cells. In this case, it refers to the absence or severe decrease of granulocytes.
Definition
Agranulocytosis is a condition that occurs when the body does not have enough granulocytes, a type of white blood cell. Granulocytes are crucial for the immune system as they help fight off infections. Agranulocytosis can be caused by various factors, including certain medications, chemotherapy, radiation therapy, and some diseases.
Symptoms
Symptoms of agranulocytosis may include sudden fever, chills, sore throat, and other signs of infection. Due to the lack of granulocytes, the body is more susceptible to infections, which can be severe and life-threatening.
Causes
Agranulocytosis can be caused by a variety of factors, including:
- Certain medications, such as antipsychotics, antithyroid drugs, and chemotherapy drugs
- Radiation therapy
- Certain diseases, such as lupus, rheumatoid arthritis, and other autoimmune diseases
- Bone marrow disorders
- Genetic disorders
Treatment
Treatment for agranulocytosis typically involves addressing the underlying cause. This may involve discontinuing the medication causing the condition, treating the disease causing the condition, or in severe cases, a bone marrow transplant may be necessary.
Related Terms
External links
- Medical encyclopedia article on Agranulocytosis
- Wikipedia's article - Agranulocytosis
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